Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
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Role of HLA Adaptation in HIV EvolutionVaccine design for CD8 T lymphocyte responsesProfile of a serial killer: cellular and molecular approaches to study individual cytotoxic T-cells following therapeutic vaccination.A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV controlImpact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacityFine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African AmericansTemporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression.Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire.Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen.
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Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Minor viral and host genetic p ...... -specific CD8 T-cell response.
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Minor viral and host genetic p ...... -specific CD8 T-cell response.
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type
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Minor viral and host genetic p ...... -specific CD8 T-cell response.
@en
Minor viral and host genetic p ...... -specific CD8 T-cell response.
@nl
prefLabel
Minor viral and host genetic p ...... -specific CD8 T-cell response.
@en
Minor viral and host genetic p ...... -specific CD8 T-cell response.
@nl
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Minor viral and host genetic p ...... -specific CD8 T-cell response.
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Alexandra Schuetz
Constantinos Petrovas
Daniel C Douek
David R Ambrozak
Emma Gostick
Gustavo Kijak
Ian S Metzler
Njabulo Ngwenyama
Richard A Koup
Tedi E Asher
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10.1182/BLOOD-2009-02-206193
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2009-06-19T00:00:00Z