Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
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DNA damage, tumor mutational load and their impact on immune responses against cancerNeoantigen-based cancer immunotherapyMechanisms of immune evasion and current status of checkpoint inhibitors in non-small cell lung cancerMeningioma Genomics: Diagnostic, Prognostic, and Therapeutic Applications.Profile of nivolumab in the treatment of metastatic squamous non-small-cell lung cancerGenomic alterations and molecular subtypes of gastric cancers in AsiansImmunotherapy for lung cancerCancer immunotherapy: the beginning of the end of cancer?Advances in immunotherapy for melanomaNovel technologies and emerging biomarkers for personalized cancer immunotherapyUnderstanding the Impact of ErbB Activating Events and Signal Transduction on Antigen Processing and Presentation: MHC Expression as a Model.Technological considerations for genome-guided diagnosis and management of cancerHigh-content molecular profiling of T-cell therapy in oncologyRecent advances in understanding antitumor immunityImmunotherapy in human colorectal cancer: Challenges and prospectiveMolecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future PerspectiveBiomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and othersThe genetics of uveal melanoma: current insightsValidation of biomarkers to predict response to immunotherapy in cancer: Volume I - pre-analytical and analytical validationThe role of immune checkpoint inhibition in the treatment of ovarian cancerCANCER. The odds of immunotherapy successIdentification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia.Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial.Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trialUnsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide-HLA Interactions.T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.Twelve-year survival and immune correlates in dendritic cell-vaccinated melanoma patients.The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.Prediction and prioritization of neoantigens: integration of RNA sequencing data with whole-exome sequencing.A phase 2 study of alisertib (MLN8237) in recurrent or persistent uterine leiomyosarcoma: An NRG Oncology/Gynecologic Oncology Group study 0231D.Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burdenImmunotherapy in genitourinary malignancies.Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with recurrent carcinoma of the anal canal.Genomic analysis and clinical management of adolescent cutaneous melanoma.Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapyThe role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcomeDriving CAR T-cells forwardTranslating RNA sequencing into clinical diagnostics: opportunities and challenges.Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy.
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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 10 September 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@en
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@nl
type
label
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@en
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@nl
altLabel
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
@en
prefLabel
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@en
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@nl
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P2860
P50
P356
P1433
P1476
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
@en
P2093
Bastian Schilling
Benjamin Weide
Carmen Loquai
Catherine J Wu
Christian Blank
Diana Miao
Eliezer M Van Allen
Jessica C Hassel
Jochen Utikal
Katharina C Kaehler
P2860
P304
P356
10.1126/SCIENCE.AAD0095
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P577
2015-09-10T00:00:00Z