Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: protection by nifedipine.
about
High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunitGlucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cellsQuantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cellsNifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction.On a sugary-relationship between caspases and lamins.Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: reversal of such metabolic defects by metformin.
P2860
Q28584125-524900AC-A411-48A5-8A90-917B42443509Q34476251-FA326B21-1901-4E43-AF8F-5A5A29578687Q38794957-E8E99A2C-649E-4560-8653-262913772287Q38974102-D7EF3063-87F2-4FC3-8044-BC68740D31FFQ39137143-77185EE4-5F37-4940-BB0F-19D41ADB68C0Q43211140-5018E7F5-2A77-4B9D-B72A-1B934DBFBDADQ46552337-4128A858-E752-440A-BEB3-29771A8191C4
P2860
Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: protection by nifedipine.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 August 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@en
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@nl
type
label
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@en
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@nl
prefLabel
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@en
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@nl
P2093
P2860
P1476
Glucotoxic conditions induce e ...... lls: protection by nifedipine.
@en
P2093
Abiy M Mohammed
Anjaneyulu Kowluru
Daleep K Arora
Khadija Syeda
P2860
P304
P356
10.1016/J.BCP.2013.08.023
P407
P577
2013-08-27T00:00:00Z