Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
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Predominant Role of Plasmacytoid Dendritic Cells in Stimulating Systemic AutoimmunityAge-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic ImmunityAutoantibodies in systemic autoimmune diseases: specificity and pathogenicityTargeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signalingHumanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus.Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen.Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndromeB cell autophagy mediates TLR7-dependent autoimmunity and inflammation.Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells.Beyond apoptosis in lupus.The potential role of retroviruses in autoimmunity.Dysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus.Associations of Autoimmunity, Immunodeficiency, Lymphomagenesis, and Gut Microbiota in Mice with Knockins for a Pathogenic Autoantibody.Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes.Nitric oxide regulates BAFF expression and T cell-independent antibody responsesPhenotyping of autoreactive B cells with labeled nucleosomes in 56R transgenic mice.Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development.Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization.Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria.Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice.Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance.CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predispositionSystemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B CellsCD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity
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Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 21 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Overexpression of TLR7 promote ...... on by transitional T1 B cells.
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Overexpression of TLR7 promote ...... on by transitional T1 B cells.
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Overexpression of TLR7 promote ...... on by transitional T1 B cells.
@en
Overexpression of TLR7 promote ...... on by transitional T1 B cells.
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Overexpression of TLR7 promote ...... on by transitional T1 B cells.
@en
Overexpression of TLR7 promote ...... on by transitional T1 B cells.
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P2093
P2860
P921
P356
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Overexpression of TLR7 promote ...... on by transitional T1 B cells.
@en
P2093
Alice E Wiedeman
Craig P Chappell
Jessica A Hamerman
Keith B Elkon
Lena Tanaka
Natalia V Giltiay
Nikita Kolhatkar
Thereza Imanishi-Kari
Thomas H Teal
P2860
P304
P356
10.1084/JEM.20122798
P407
P577
2013-10-21T00:00:00Z