Polo-like kinase 1 reaches beyond mitosis--cytokinesis, DNA damage response, and development.
about
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separasePlk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionPolo-like kinase 1, on the rise from cell cycle regulation to prostate cancer developmentWhat goes on must come off: phosphatases gate-crash the DNA damage responseMolecular dynamics of PLK1 during mitosisPLK1, A Potential Target for Cancer TherapyPolo-like kinase and its inhibitors: Ready for the match to start?The MRN-CtIP pathway is required for metaphase chromosome alignment.Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formationA two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells.Mechanisms underlying Plk1 polo-box domain-mediated biological processes and their physiological significance.Association of p21 with NF-YA suppresses the expression of Polo-like kinase 1 and prevents mitotic death in response to DNA damage.Targeting prostate cancer cell lines with polo-like kinase 1 inhibitors as a single agent and in combination with histone deacetylase inhibitorsThe transcription factor YY1 is a substrate for Polo-like kinase 1 at the G2/M transition of the cell cycle.Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replicationPolo-box domain: a versatile mediator of polo-like kinase function.Plk1-targeted small molecule inhibitors: molecular basis for their potency and specificity.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.Polo-like kinase-activating kinases: Aurora A, Aurora B and what else?Breast cancer biomarker discovery in the functional genomic age: a systematic review of 42 gene expression signatures.Estrogen induced breast cancer is the result in the disruption of the asymmetric cell division of the stem cell.Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy.ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT.Identification of potential Plk1 targets in a cell-cycle specific proteome through structural dynamics of kinase and Polo box-mediated interactionsMammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochoresNFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpointMammalian Polo-like kinase 1 (Plk1) promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1·CENP-Q complex from kinetochores.Greatwall and Polo-like kinase 1 coordinate to promote checkpoint recoveryPolo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formationPhosphorylation of right open reading frame 2 (Rio2) protein kinase by polo-like kinase 1 regulates mitotic progressionCilia and cell cycle re-entry: more than a coincidence.Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics.Rational Combinations of Targeted Agents in AMLPlk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair.Centrosomal protein 55 (Cep55) stability is negatively regulated by p53 protein through Polo-like kinase 1 (Plk1)Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty.Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells
P2860
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P2860
Polo-like kinase 1 reaches beyond mitosis--cytokinesis, DNA damage response, and development.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Polo-like kinase 1 reaches bey ...... age response, and development.
@en
Polo-like kinase 1 reaches bey ...... age response, and development.
@nl
type
label
Polo-like kinase 1 reaches bey ...... age response, and development.
@en
Polo-like kinase 1 reaches bey ...... age response, and development.
@nl
prefLabel
Polo-like kinase 1 reaches bey ...... age response, and development.
@en
Polo-like kinase 1 reaches bey ...... age response, and development.
@nl
P1476
Polo-like kinase 1 reaches bey ...... age response, and development.
@en
P2093
Kristina Trenz
Tohru Takaki
P304
P356
10.1016/J.CEB.2008.10.005
P577
2008-11-27T00:00:00Z