Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics.
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Novel mitochondrial targets for neuroprotectionTargeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunitiesAn effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulaeSex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation.A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in miceHyperglycemia / hypoglycemia-induced mitochondrial dysfunction and cerebral ischemic damage in diabeticsPaeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs/NF-κB-mediated inflammatory responses.Alternative mitochondrial electron transfer as a novel strategy for neuroprotection.An active component of Achyranthes bidentata polypeptides provides neuroprotection through inhibition of mitochondrial-dependent apoptotic pathway in cultured neurons and in animal models of cerebral ischemiaRoles of oxidative stress, apoptosis, PGC-1α and mitochondrial biogenesis in cerebral ischemia.Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions.Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells.Mitochondrial distribution of neuroglobin and its response to oxygen-glucose deprivation in primary-cultured mouse cortical neurons.Intravenous Treatment with a Long-Chain Omega-3 Lipid Emulsion Provides Neuroprotection in a Murine Model of Ischemic Stroke - A Pilot StudyDisruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats.Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathyMitophagy in ischaemia/reperfusion induced cerebral injury.Mitochondrial mechanisms of neuroglobin's neuroprotection.Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries.Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage.Neuroprotection against permanent focal cerebral ischemia by ginkgolides A and B is associated with obstruction of the mitochondrial apoptotic pathway via inhibition of c-Jun N-terminal kinase in rats.The role of neuroglobin in the neuroprotection of limb ischemic preconditioning in rats.Therapeutic Potential of Novel Twin Compounds Containing Tetramethylpyrazine and Carnitine Substructures in Experimental Ischemic Stroke.Dynamic changes of mitochondrial fusion and fission proteins after transient cerebral ischemia in mice.Diverse roles of mitochondria in ischemic stroke.Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production.Inhibition of excessive autophagy and mitophagy mediates neuroprotective effects of URB597 against chronic cerebral hypoperfusion.Mitochondria in Ischemic Stroke: New Insight and ImplicationsEmerging Roles of Sonic Hedgehog in Adult Neurological Diseases: Neurogenesis and Beyond
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Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mitochondrial targets for stro ...... lly translatable therapeutics.
@en
Mitochondrial targets for stro ...... lly translatable therapeutics.
@nl
type
label
Mitochondrial targets for stro ...... lly translatable therapeutics.
@en
Mitochondrial targets for stro ...... lly translatable therapeutics.
@nl
prefLabel
Mitochondrial targets for stro ...... lly translatable therapeutics.
@en
Mitochondrial targets for stro ...... lly translatable therapeutics.
@nl
P2093
P2860
P1433
P1476
Mitochondrial targets for stro ...... lly translatable therapeutics.
@en
P2093
Lawrence R Wechsler
Peter S Vosler
Steven H Graham
P2860
P304
P356
10.1161/STROKEAHA.108.543769
P407
P577
2009-05-28T00:00:00Z