Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes. - Wikidata - awgldk - TriplyDB

Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.

Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.

http://www.wikidata.org/entity/Q37325576

about

Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo.Microsomal cytochrome P450 as a target for drug discovery and repurposing.Arachidonic Acid Metabolism by Human Cardiovascular CYP2J2 Is Modulated by Doxorubicin.Angiotensin II Receptor Blockers Inhibit the Generation of Epoxyeicosatrienoic Acid from Arachidonic Acid in Recombinant CYP2C9, CYP2J2 and Human Liver Microsomes.Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine.CYP2J2 expression in adult ventricular myocytes protects against external and drug induced ROS toxicity.CYP2J2 - regulation, function and polymorphism.

P2860

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P2860

Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.

http://www.wikidata.org/entity/Q37325576

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 September 2013

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Activity, inhibition, and indu ...... human primary cardiomyocytes.

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Activity, inhibition, and indu ...... human primary cardiomyocytes.

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type

label

Activity, inhibition, and indu ...... human primary cardiomyocytes.

@en

Activity, inhibition, and indu ...... human primary cardiomyocytes.

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prefLabel

Activity, inhibition, and indu ...... human primary cardiomyocytes.

@en

Activity, inhibition, and indu ...... human primary cardiomyocytes.

@nl

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Drug Metabolism and Disposition

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Activity, inhibition, and indu ...... human primary cardiomyocytes.

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Eric A Evangelista

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J P Jones

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Nahush A Mokadam

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Rheem A Totah

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Rüdiger Kaspera

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P2860

Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart

Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine

Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2

Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole

CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes

Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism

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2087-2094

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scholarly article

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10.1124/DMD.113.053389

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12

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2013-09-10T00:00:00Z

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24021950

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3834129

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