Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells.

Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells.

Item
http://www.wikidata.org/entity/Q37327269
Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyCheckpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x.Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase.Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocksCdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells.Selective tumor killing based on specific DNA-damage response deficiencies.DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic StabilityProspects for the Use of ATR Inhibitors to Treat Cancer.P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance.Persimmon leaf extract inhibits the ATM activity during DNA damage response induced by Doxorubicin in A549 lung adenocarcinoma cells.Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors
P2860

Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells.

Item
http://www.wikidata.org/entity/Q37327269
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@en
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@nl
type
label
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@en
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@nl
prefLabel
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@en
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Reduced ATR or Chk1 expression ...... cient colorectal cancer cells.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
P932