The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice.
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Functional Amyloid Signaling via the Inflammasome, Necrosome, and Signalosome: New Therapeutic Targets in Heart FailureProteasomal and lysosomal protein degradation and heart disease.The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicityNeddylation and deneddylation in cardiac biologyThe COP9 signalosome and cullin-RING ligases in the heartThe COP9 signalosome and vascular function: intriguing possibilities?NEDD8 Ultimate Buster 1 Long (NUB1L) Protein Suppresses Atypical Neddylation and Promotes the Proteasomal Degradation of Misfolded Proteins.COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.Posttranslational modifications of lysine and evolving role in heart pathologies-recent developments.Murine Myocardial Transcriptome Analysis Reveals a Critical Role of COPS8 in the Gene Expression of Cullin-RING Ligase Substrate Receptors and Redox and Vesicle Trafficking Pathways.Ubiquitin and ubiquitin-like proteins in cardiac disease and protection.Roles of Multifunctional COP9 Signalosome Complex in Cell Fate and Implications for Drug Discovery.Autophagy modulation: a potential therapeutic approach in cardiac hypertrophy.Bone fracture in a rat femoral fracture model is associated with the activation of autophagy.SUMOylation: a novel protein quality control modifier in the heart.TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux.Systemic inhibition of neddylation by 3-day MLN4924 treatment regime does not impair autophagic flux in mouse hearts and brains.The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure.Csn5 Is Required for the Conidiogenesis and Pathogenesis of the Alternaria alternata Tangerine Pathotype.Application of Mesenchymal Stem Cells for Therapeutic Agent Delivery in Anti-tumor Treatment.Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
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The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@en
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@nl
type
label
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@en
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@nl
prefLabel
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@en
The COP9 signalosome is requir ...... yocyte survival in adult mice.
@nl
P2093
P2860
P1476
The COP9 signalosome is requir ...... myocyte survival in adult mice
@en
P2093
Hanna Osinska
Jeffrey Robbins
Jinbao Liu
P2860
P304
P356
10.1161/CIRCHEARTFAILURE.113.000338
P50
P577
2013-07-19T00:00:00Z