MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
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N(6)-methyladenosine Modulates Messenger RNA Translation EfficiencyPhenotypic noise: effects of post-transcriptional regulatory processes affecting mRNAClk post-transcriptional control denoises circadian transcription both temporally and spatially.An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noiseMicroRNAs and their roles in developmental canalization.Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages.MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.miRNAs at the interface of cellular stress and diseasemiR-107 activates ATR/Chk1 pathway and suppress cervical cancer invasion by targeting MCL1.PHA-4/FOXA-regulated microRNA feed forward loops during Caenorhabditis elegans dietary restriction.Editorial for "Regulatory RNAs in the nervous system".Transcription factor and microRNA-regulated network motifs for cancer and signal transduction networks.Mathematical modeling of combinatorial regulation suggests that apparent positive regulation of targets by miRNA could be an artifact resulting from competition for mRNAModel-guided quantitative analysis of microRNA-mediated regulation on competing endogenous RNAs using a synthetic gene circuit.microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.Probing the Limits to MicroRNA-Mediated Control of Gene Expression.No Evidence that MicroRNAs Coevolve with Genes Located in Copy Number RegionsFibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles.miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in MiceNoise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited.The Switch in a Genetic Toggle System with Lévy Noise.Evolving insights into RNA modifications and their functional diversity in the brain.MiRNAs in β-Cell Development, Identity, and Disease.Understanding microRNA-mediated gene regulatory networks through mathematical modelling.ceRNA crosstalk stabilizes protein expression and affects the correlation pattern of interacting proteins.Pervasive robustness in biological systems.The developmental genetics of biological robustness.MicroRNA regulation of macrophages in human pathologies.MicroRNAs Provide Feedback Regulation of Epithelial-Mesenchymal Transition Induced by Growth Factors.MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle.A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri.MicroRNA-320 suppresses cervical cancer cell viability, migration and invasion via directly targeting FOXM1.Regulation of microRNA expression in the neuronal stem cell niches during aging of the short-lived annual fish Nothobranchius furzeri.Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells.Synergic Functions of miRNAs Determine Neuronal Fate of Adult Neural Stem Cells.The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells.MicroRNA expression during demosponge dissociation, reaggregation, and differentiation and a evolutionarily conserved demosponge miRNA expression profile.Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status.Comprehensive network of miRNA-induced intergenic interactions and a biological role of its core in cancer.
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MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
@en
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
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MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
@en
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
@nl
prefLabel
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
@en
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.
@nl
P2093
P2860
P356
P1476
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise
@en
P2093
Chiara Fracassi
Immacolata Garzilli
Simona Ventre
Stefania Criscuolo
P2860
P2888
P356
10.1038/NCOMMS3364
P407
P577
2013-01-01T00:00:00Z