Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
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Molecular mechanisms of chemopreventive phytochemicals against gastroenterological cancer developmentLifestyle Modifications and Colorectal CancerResearch progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanismsTherapeutic implications of curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathways.The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cellsmiR-21 and miR-145 cooperation in regulation of colon cancer stem cells.MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells.Regulation of colon cancer recurrence and development of therapeutic strategies.Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy.Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.Cancer-linked targets modulated by curcuminChemoprevention of gastrointestinal cancer: the reality and the dream.Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens.MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.Prevention and Treatment of Colorectal Cancer by Natural Agents From Mother Nature.Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model.Insulin-like growth factor: current concepts and new developments in cancer therapy.New insights into therapeutic activity and anticancer properties of curcumin.Therapeutic potential of curcumin in gastrointestinal diseases.Cancer Stem Cells: A Moving TargetThe aryl hydrocarbon receptor as an antitumor target of synthetic curcuminoids in colorectal cancer.Effect of curcumin on vascular endothelial growth factor in hypoxic HepG2 cells via the insulin-like growth factor 1 receptor signaling pathway.
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P2860
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@en
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
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type
label
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@en
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@nl
prefLabel
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@en
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@nl
P2093
P2860
P1433
P1476
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
@en
P2093
Adhip P N Majumdar
Althea A Elliott
Bhaumik B Patel
Deepshika Gupta
Vivek Sengupta
Yingjie Yu
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P304
P407
P577
2010-02-01T00:00:00Z