In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.
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Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancyPreclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug CandidateA genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in KenyaTemporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal KenyaMicrobial genomics and antimicrobial susceptibility testing.Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax.A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.Molecular epidemiology of Plasmodium vivax anti-folate resistance in India.In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparumReduced impact of pyrimethamine drug pressure on Plasmodium malariae dihydrofolate reductase gene.Prevalence of Dihydrofolate reductase gene mutations in Plasmodium falciparum isolate from pregnant women in Nigeria.Antimalarial drugs: modes of action and mechanisms of parasite resistance.Drug repositioning in the treatment of malaria and TB.Mutual action of anticancer and antiparasitic drugs: are there any shared targets?Antiplasmodial drug targets: a patent review (2000 - 2013).Preclinical drug evaluation system in the Plasmodium knowlesi baboon model of malaria: the methotrexate study.Parasites and cancers: parasite antigens as possible targets for cancer immunotherapy.MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.Anticancer agents against malaria: time to revisit?Vivax malaria: old drug, new uses?High prevalence of dihydrofolate reductase gene mutations in Plasmodium falciparum parasites among pregnant women in Nigeria after reported use of sulfadoxine-pyrimethamine.Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts.Current and Future Strategies for Improving Drug Discovery Efficiency
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In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@en
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@nl
type
label
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@en
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@nl
prefLabel
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@en
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@nl
P2093
P2860
P356
P1476
In vitro activity of antifolat ...... tes with Ile-164-Leu mutation.
@en
P2093
Alexis Nzila
Isabella Ochola
John Okombo
Steven M Kiara
Victor Masseno
P2860
P304
P356
10.1128/AAC.00308-09
P407
P577
2009-06-15T00:00:00Z