The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity.
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The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth.Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathwaySystematic analysis of time-series gene expression data on tumor cell-selective apoptotic responses to HDAC inhibitors.A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myelomaQuinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells.SC06, a novel small molecule compound, displays preclinical activity against multiple myeloma by disrupting the mTOR signaling pathwayClass III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanomaThe Ring Finger Protein RNF6 Induces Leukemia Cell Proliferation as a Direct Target of Pre-B-cell Leukemia Homeobox 1A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathwayAn inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathwayStructural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity.Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.Combination treatment with fasudil and clioquinol produces synergistic anti-tumor effects in U87 glioblastoma cells by activating apoptosis and autophagy.
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P2860
The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 10 October 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The antiparasitic clioquinol i ...... histone deacetylase activity.
@en
The antiparasitic clioquinol i ...... histone deacetylase activity.
@nl
type
label
The antiparasitic clioquinol i ...... histone deacetylase activity.
@en
The antiparasitic clioquinol i ...... histone deacetylase activity.
@nl
prefLabel
The antiparasitic clioquinol i ...... histone deacetylase activity.
@en
The antiparasitic clioquinol i ...... histone deacetylase activity.
@nl
P2093
P2860
P356
P1476
The antiparasitic clioquinol i ...... histone deacetylase activity.
@en
P2093
Aining Sun
Chunhua Qiao
Jingyu Zhu
Kunkun Han
Mingyun Shen
Suning Chen
Xiaowen Tang
P2860
P304
34181-34189
P356
10.1074/JBC.M113.472563
P407
P50
P577
2013-10-10T00:00:00Z