Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
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Cross-presentation of IgG-containing immune complexesThe Role of FcRn in Antigen PresentationUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsTargeting FcRn for the modulation of antibody dynamicsThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyFcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodiesCharacterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRnThe effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics.Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applicationsAlteration of the N-glycome of bovine milk glycoproteins during early lactation.IgG subclasses and allotypes: from structure to effector functions.FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen.Transgenic rabbits that overexpress the neonatal Fc receptor (FcRn) generate higher quantities and improved qualities of anti-thymocyte globulin (ATG).A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection.Efficient mucosal vaccination mediated by the neonatal Fc receptor.Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies.Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen.Antibodies and their receptors: different potential roles in mucosal defense.Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice.N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice.NFκB induces overexpression of bovine FcRn: a novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn.Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'.The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases.Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumptionEngineering immunity in the mucosal niche against sexually transmitted infections.Accelerating antibody discovery using transgenic animals overexpressing the neonatal Fc receptor as a result of augmented humoral immunity.Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential.Intranasal administration of antibody-bound respiratory syncytial virus particles efficiently primes virus-specific immune responses in mice.Keystone Symposium on Antibodies as Drugs: March 27-April 1, 2009, Whistler, BC CA.Nanomaterials for cancer immunotherapy.Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells.
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Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@en
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@nl
type
label
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@en
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@nl
prefLabel
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@en
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
@nl
P2093
P2860
P1476
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments
@en
P2093
Beatrix Pickl-Herk
Su-Tang Lo
Sylvia Wanjie
P2860
P304
P356
10.4049/JIMMUNOL.181.11.7550
P407
P577
2008-12-01T00:00:00Z