Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases
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Dissecting the genetics of complex traits using summary association statisticsLeveraging functional annotations in genetic risk prediction for human complex diseases.Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk predictionColocalization of GWAS and eQTL Signals Detects Target Genes.cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes.Epigenetic Combinatorial Patterns Predict Disease VariantsReview: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential.Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation.Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies.Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies.Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.Pleiotropic Mapping and Annotation Selection in Genome-wide Association Studies with Penalized Gaussian Mixture Models.A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics.Current Scope and Challenges in Phenome-Wide Association Studies.Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.Cellular network perturbations by disease-associated variants.A unifying framework for joint trait analysis under a non-infinitesimal model.
P2860
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P2860
Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 July 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Joint Bayesian inference of ri ...... ultiple complex human diseases
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Joint Bayesian inference of ri ...... ltiple complex human diseases.
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type
label
Joint Bayesian inference of ri ...... ultiple complex human diseases
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Joint Bayesian inference of ri ...... ltiple complex human diseases.
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prefLabel
Joint Bayesian inference of ri ...... ultiple complex human diseases
@en
Joint Bayesian inference of ri ...... ltiple complex human diseases.
@nl
P2860
P356
P1476
Joint Bayesian inference of ri ...... ultiple complex human diseases
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P2093
P2860
P356
10.1093/NAR/GKW627
P407
P577
2016-07-12T00:00:00Z