The establishment of gene silencing at single-cell resolution.
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Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generationsHeterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNAThe role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin stateCompetition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin.The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressorOncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases.Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.Epigenetics in Saccharomyces cerevisiae.The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylationPromoter strength influences the S phase requirement for establishment of silencing at the Saccharomyces cerevisiae silent mating type LociProliferating cell nuclear antigen (PCNA) is required for cell cycle-regulated silent chromatin on replicated and nonreplicated genes.Symmetry, asymmetry, and kinetics of silencing establishment in Saccharomyces cerevisiae revealed by single-cell optical assaysDot1 and histone H3K79 methylation in natural telomeric and HM silencingHeritable capture of heterochromatin dynamics in Saccharomyces cerevisiae.A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.Mating-type genes and MAT switching in Saccharomyces cerevisiae.Sir3 and epigenetic inheritance of silent chromatin in Saccharomyces cerevisiae.Cooperative stabilization of the SIR complex provides robust epigenetic memory in a model of SIR silencing in Saccharomyces cerevisiae.Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatinThe enigmatic conservation of a Rap1 binding site in the Saccharomyces cerevisiae HMR-E silencer.Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation.Open chromatin in pluripotency and reprogrammingThe histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.Dare to challenge the silence? Telomeric gene silencing revisited.Progressive methylation of ageing histones by Dot1 functions as a timer.A Matter of Scale and Dimensions: Chromatin of Chromosome Landmarks in the Fungi.The Putative Histone Methyltransferase DOT1 Regulates Aflatoxin and Pathogenicity Attributes in Aspergillus flavus.Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae.A common telomeric gene silencing assay is affected by nucleotide metabolism.Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.Donor Preference Meets Heterochromatin: Moonlighting Activities of a Recombinational Enhancer in Saccharomyces cerevisiae.Detection of an altered heterochromatin structure in the absence of the nucleotide excision repair protein Rad4 in Saccharomyces cerevisiae.Recruitment and allosteric stimulation of a histone deubiquitinating enzyme during heterochromatin assembly.Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast.The interplay of histone H2B ubiquitination with budding and fission yeast heterochromatin.Impact of Homologous Recombination on Silent Chromatin in Saccharomyces cerevisiae.Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability
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The establishment of gene silencing at single-cell resolution.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 21 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The establishment of gene silencing at single-cell resolution.
@en
The establishment of gene silencing at single-cell resolution.
@nl
type
label
The establishment of gene silencing at single-cell resolution.
@en
The establishment of gene silencing at single-cell resolution.
@nl
prefLabel
The establishment of gene silencing at single-cell resolution.
@en
The establishment of gene silencing at single-cell resolution.
@nl
P2860
P356
P1433
P1476
The establishment of gene silencing at single-cell resolution.
@en
P2093
Jasper Rine
Sandrine Dudoit
P2860
P2888
P304
P356
10.1038/NG.402
P407
P50
P577
2009-06-21T00:00:00Z