Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.
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Life of T follicular helper cellsProtective neutralizing influenza antibody response in the absence of T follicular helper cells.Class-switched memory B cells remodel BCRs within secondary germinal centers.A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve.Generation of memory B cells inside and outside germinal centers.Role of germinal centers for the induction of broadly-reactive memory B cells.Rapid development of broadly influenza neutralizing antibodies through redundant mutations.
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Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
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type
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
@en
Both mutated and unmutated mem ...... ted to the secondary stimulus.
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
@nl
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Both mutated and unmutated mem ...... ted to the secondary stimulus.
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Akiko Ishige
Itsumi Toyokura
Mariko Okada
Masaki Nomura
Michiko Shimoda
Tomohiro Kaji
Toshitada Takemori
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P304
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10.1093/INTIMM/DXT030
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2013-09-10T00:00:00Z