The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels. - Wikidata - awgldk - TriplyDB

The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels.

The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels.

http://www.wikidata.org/entity/Q37339236

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Human muscle economy myoblast differentiation and excitation-contraction coupling use the same molecular partners, STIM1 and STIM2 STIM proteins: dynamic calcium signal transducers Multifaceted roles of STIM proteins Stanniocalcin 2 is a negative modulator of store-operated calcium entry Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons STIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca2+ signaling after wounding.The role of calcium release activated calcium channels in osteoclast differentiation.STIM proteins and the endoplasmic reticulum-plasma membrane junctions.Activation and regulation of store-operated calcium entry.STIM1L is a new actin-binding splice variant involved in fast repetitive Ca2+ release.WT1/EGR1-mediated control of STIM1 expression and function in cancer cells Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complex Control of type I interferon-induced cell death by Orai1-mediated calcium entry in T cells Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive Melanoma.Different agonists recruit different stromal interaction molecule proteins to support cytoplasmic Ca2+ oscillations and gene expression Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca²+ signaling by differentially modulating STIM1 and STIM2.Sensing cellular stress through STIM proteins.Pore waters regulate ion permeation in a calcium release-activated calcium channel.Orais and STIMs: physiological mechanisms and disease STIM proteins: integrators of signalling pathways in development, differentiation and disease.STIM and Orai: dynamic intermembrane coupling to control cellular calcium signals.An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs.Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1).Partial unfolding and oligomerization of stromal interaction molecules as an initiation mechanism of store operated calcium entry.Unraveling STIM2 function.Loss of endoplasmic reticulum Ca2+ homeostasis: contribution to neuronal cell death during cerebral ischemia.STIM proteins, Orai1 and gene expression.Molecular pharmacology of store-operated CRAC channels.Structural and functional mechanisms of CRAC channel regulation.Role of Calcium Signaling in B Cell Activation and Biology.Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.Role of STIM2 in cell function and physiopathology.STIM1 is required for attenuation of PMCA-mediated Ca2+ clearance during T-cell activation The calcium store sensor, STIM1, reciprocally controls Orai and CaV1.2 channels.Calcium signals: STIM dynamics mediate spatially unique oscillations.Wilms tumor suppressor 1 (WT1) and early growth response 1 (EGR1) are regulators of STIM1 expression.STIM1 and STIM2 proteins differently regulate endogenous store-operated channels in HEK293 cells.A cytosolic STIM2 preprotein created by signal peptide inefficiency activates ORAI1 in a store-independent manner.STIM2 regulates both intracellular Ca2+ distribution and Ca2+ movement in skeletal myotubes.The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complex.

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The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels.

http://www.wikidata.org/entity/Q37339236

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@en

The short N-terminal domains o ...... on kinetics of Orai1 channels.

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type

label

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@en

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@nl

prefLabel

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@en

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@nl

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JBC.C109.010900

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Journal of Biological Chemistry

P1476

The short N-terminal domains o ...... on kinetics of Orai1 channels.

@en

P2093

Chanyu Yue

http://www.w3.org/2001/XMLSchema#string

Donald L Gill

http://www.w3.org/2001/XMLSchema#string

Jonathan Soboloff

http://www.w3.org/2001/XMLSchema#string

Michael Ritchie

http://www.w3.org/2001/XMLSchema#string

Salvatore Mancarella

http://www.w3.org/2001/XMLSchema#string

Yandong Zhou

http://www.w3.org/2001/XMLSchema#string

Youjun Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins

Orai1 and STIM reconstitute store-operated calcium channel function

STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation

STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry

STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels

Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

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19164-19168

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scholarly article

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10.1074/JBC.C109.010900

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29

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284

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2009-06-01T00:00:00Z

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19487696

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2740537

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