The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity. - Wikidata - awgldk - TriplyDB

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

http://www.wikidata.org/entity/Q37340475

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IDO2 in Immunomodulation and Autoimmune Disease IDO2: A Pathogenic Mediator of Inflammatory Autoimmunity Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism Systemic treatment with CpG-B after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (IDO).Bin1 attenuation suppresses experimental colitis by enforcing intestinal barrier function.A powerful yeast-based screening assay for the identification of inhibitors of indoleamine 2,3-dioxygenase.IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis.Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer 1-Methyl-tryptophan synergizes with methotrexate to alleviate arthritis in a mouse model of arthritis.The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists.Inhibitors of indoleamine 2,3-dioxygenase: a review of novel patented lead compounds.N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.Molecular characterization of subcutaneous panniculitis-like T-cell lymphoma reveals upregulation of immunosuppression- and autoimmunity-associated genes.Plasma kynurenic acid concentration in patients undergoing cardiac surgery: effect of anaesthesia.Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate.Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases.Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration.Addition of an indoleamine 2,3,-dioxygenase inhibitor to B cell-depletion therapy blocks autoreactive B cell activation and recurrence of arthritis in K/BxN mice.B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens.The potential role of indoleamine 2,3 dioxygenase (IDO) as a predictive and therapeutic target for diabetes treatment: a mythical truth.Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege IDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism.Allergic disease: understanding how in utero events set the scene.Tryptophan metabolism, from nutrition to potential therapeutic applications.Herbal medicinal products target defined biochemical and molecular mediators of inflammatory autoimmune arthritis.Indoleamine 2,3-dioxygenase: from catalyst to signaling function.Exploitation of the IDO Pathway in the Therapy of Rheumatoid Arthritis.Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment.Pharmacogenetics of major depressive disorder: top genes and pathways toward clinical applications.Induction of hepatitis B virus surface antigen-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity.Indoleamine 2,3-dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and is Associated with Type II Hypersensitivity/Autoimmunity.A perspective on new immune adjuvant principles: Reprogramming inflammatory states to permit clearance of cancer cells and other age-associated cellular pathologies B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury.Indoleamine 2,3-Dioxygenase Is Dispensable for The Immunomodulatory Function of Stem Cells from Human Exfoliated Deciduous Teeth.Pathogenic antibodies are active participants in spinal cord injury.Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation.RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus.Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis.

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The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

http://www.wikidata.org/entity/Q37340475

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@en

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@nl

type

label

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@en

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@nl

prefLabel

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@en

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

@nl

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JIMMUNOL.0804328

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Journal of Immunology

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The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

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Elizabeth Pigott

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George C Prendergast

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Grant N Scott

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James DuHadaway

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Laura Mandik-Nayak

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Natalie Ridge

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P2860

Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

Prevention of allogeneic fetal rejection by tryptophan catabolism

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Inhibition of T cell proliferation by macrophage tryptophan catabolism

Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation

Cytokines in the pathogenesis of rheumatoid arthritis

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

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12

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182

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Alexander J Muller

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2009-06-01T00:00:00Z

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26264680

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