The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats. - Wikidata - awgldk - TriplyDB

The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats.

The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats.

http://www.wikidata.org/entity/Q37341623

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Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications Behavioral and neurochemical effects of chronic L-DOPA treatment on nonmotor sequelae in the hemiparkinsonian rat.The CB1 cannabinoid receptor agonist reduces L-DOPA-induced motor fluctuation and ERK1/2 phosphorylation in 6-OHDA-lesioned rats Side effect profile of 5-HT treatments for Parkinson's disease and L-DOPA-induced dyskinesia in rats.Local modulation of striatal glutamate efflux by serotonin 1A receptor stimulation in dyskinetic, hemiparkinsonian rats.Behavioral and cellular modulation of L-DOPA-induced dyskinesia by beta-adrenoceptor blockade in the 6-hydroxydopamine-lesioned rat.Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia.Presynaptic effects of levodopa and their possible role in dyskinesia.Role of the primary motor cortex in L-Dopa-induced dyskinesia and its modulation by 5-HT1A receptor stimulation.Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease.Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia.Effects of the beta-adrenergic receptor antagonist Propranolol on dyskinesia and L-DOPA-induced striatal DA efflux in the hemi-parkinsonian rat Controlled-release levodopa methyl ester/benserazide-loaded nanoparticles ameliorate levodopa-induced dyskinesia in rats.Magnetization transfer and adiabatic R 1ρ MRI in the brainstem of Parkinson's disease L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson's disease.Serotonin transporter inhibition attenuates l-DOPA-induced dyskinesia without compromising l-DOPA efficacy in hemi-parkinsonian rats Effects of 5-HT1A receptor stimulation on D1 receptor agonist-induced striatonigral activity and dyskinesia in hemiparkinsonian rats.The effects of BMY-14802 against L-DOPA- and dopamine agonist-induced dyskinesia in the hemiparkinsonian rat Nicotine-mediated improvement in L-dopa-induced dyskinesias in MPTP-lesioned monkeys is dependent on dopamine nerve terminal function α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats.Effects of L-dopa priming on cortical high beta and high gamma oscillatory activity in a rodent model of Parkinson's disease Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats Ranitidine reduced levodopa-induced dyskinesia in a rat model of Parkinson's disease.Potential mechanisms underlying anxiety and depression in Parkinson's disease: consequences of l-DOPA treatment.The serotonergic system in motor and non-motor manifestations of Parkinson's disease.Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease.Serotonin System Implication in l-DOPA-Induced Dyskinesia: From Animal Models to Clinical Investigations.Pharmacological strategies for the management of levodopa-induced dyskinesia in patients with Parkinson's disease.Role of Serotonin Neurons in L-DOPA- and Graft-Induced Dyskinesia in a Rat Model of Parkinson's Disease.The acute and long-term L-DOPA effects are independent from changes in the activity of dorsal raphe serotonergic neurons in 6-OHDA lesioned rats.Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson's disease: role of NMDA vs. 5-HT1A receptors Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.Serotonergic targets for the treatment of L-DOPA-induced dyskinesia.Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias.Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease.Serotonergic antidepressant drugs and L-dopa-induced dyskinesias in Parkinson's disease.

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The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats.

http://www.wikidata.org/entity/Q37341623

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article científic

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bilimsel makale

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scientific article published on July 2009

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The role of the dorsal raphe n ...... esia in hemiparkinsonian rats.

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The role of the dorsal raphe n ...... esia in hemiparkinsonian rats.

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The role of the dorsal raphe n ...... esia in hemiparkinsonian rats.

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The role of the dorsal raphe n ...... esia in hemiparkinsonian rats.

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Christopher Bishop

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Christopher J Barnum

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John Y Park

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Karen L Eskow

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Kristin B Dupre

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Sando O Dickinson

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P2860

Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

Activation of 5-HT(1A) but not 5-HT(1B) receptors attenuates an increase in extracellular dopamine derived from exogenously administered L-DOPA in the striatum with nigrostriatal denervation.

Post- versus presynaptic plasticity in L-DOPA-induced dyskinesia.

Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models.

Central 5-HT(1A) receptors: regional distribution and functional characteristics.

An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat.

Effects of serotonin 5-HT1A agonist in advanced Parkinson's disease.

Motor fluctuations and dyskinesias in Parkinson's disease: clinical manifestations.

The human raphe nuclei and the serotonergic system.

Translation of nondopaminergic treatments for levodopa-induced dyskinesia from MPTP-lesioned nonhuman primates to phase IIa clinical studies: keys to success and roads to failure.

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610-620

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scholarly article

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10.1002/SYN.20630

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7

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63

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2009-07-01T00:00:00Z

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19309758

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2741636

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