The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. - Wikidata - awgldk - TriplyDB

The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development.

The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development.

http://www.wikidata.org/entity/Q37342975

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Molecular control of the neural crest and peripheral nervous system development New insights on Schwann cell development Influence of stochastic gene expression on the cell survival rheostat after traumatic brain injury Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium Dual specificity phosphatase 15 regulates Erk activation in Schwann cells Loss-of-function mutations in PTPN11 cause metachondromatosis, but not Ollier disease or Maffucci syndrome.Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro.Neuronal Neuregulin 1 type III directs Schwann cell migration.Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function Transcriptional hallmarks of Noonan syndrome and Noonan-like syndrome with loose anagen hair.Signals regulating myelination in peripheral nerves and the Schwann cell response to injury.Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development α6β1 and α7β1 integrins are required in Schwann cells to sort axons.Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation.Nrg1/ErbB signaling networks in Schwann cell development and myelination.Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia.New insights into signaling during myelination in zebrafish.Axonal regulation of Schwann cell ensheathment and myelination.Signaling mechanisms regulating myelination in the central nervous system.Plastic fantastic: Schwann cells and repair of the peripheral nervous system.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons.Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.Schwann cell myelination KIAA1199: A novel regulator of MEK/ERK-induced Schwann cell dedifferentiation.Loss of Ptpn11 (Shp2) drives satellite cells into quiescence Molecular Mechanisms Involved in Schwann Cell Plasticity The role of neuregulin-1 in the response to nerve injury.Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis.Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular signaling pathways Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.Specific functions for ERK/MAPK signaling during PNS development.Control of Schwann cell myelination.Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.

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The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development.

http://www.wikidata.org/entity/Q37342975

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 11 September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The tyrosine phosphatase Shp2 ...... hout Schwann cell development.

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type

label

The tyrosine phosphatase Shp2 ...... hout Schwann cell development.

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prefLabel

The tyrosine phosphatase Shp2 ...... hout Schwann cell development.

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PNAS.0904336106

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Proceedings of the National Academy of Sciences of the United States of America

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The tyrosine phosphatase Shp2 ...... hout Schwann cell development.

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Carmen Birchmeier

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Cyril Cheret

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Florian E Paul

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Hagen Wende

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Herbert Schulz

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Katja S Grossmann

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Konstantin Feinberg

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Matthias Selbach

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Sandra Zurborg

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Walter Birchmeier

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Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor

A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation

Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew

Structural basis for the autoinhibition of focal adhesion kinase

Untangling the ErbB signalling network

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

Axonal neuregulin-1 regulates myelin sheath thickness

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16704-16709

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10.1073/PNAS.0904336106

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39

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106

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Alistair N Garratt

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2009-09-11T00:00:00Z

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26871536

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19805360

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2742405

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