A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
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Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegansFunctional anatomy of movement disordersVesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistryParkinson's disease and primate research: past, present, and futureLow dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptorMitochondrial dysfunction in Parkinson's diseaseParkinson's Disease: The Mitochondria-Iron LinkElusive roles for reactive astrocytes in neurodegenerative diseasesCatecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disordersCellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disordersParkinson's disease as a result of agingEvidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposureCellular replacement therapy for Parkinson's disease--where we are today?A key amino acid responsible for substrate selectivity of monoamine oxidase A and BAging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's diseaseThe perplexing paradox of paraquat: the case for host-based susceptibility and postulated neurodegenerative effectsChemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary cultureIdentification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease1-Methyl-4-phenyl-pyridinium time-dependently alters expressions of oxoguanine glycosylase 1 and xeroderma pigmentosum group F protein in PC12 cellsThe reward circuit: linking primate anatomy and human imagingCharacterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells.Complex I polymorphisms, bigenomic heterogeneity, and family history in Virginians with Parkinson's disease.Towards model-based control of Parkinson's disease.Abnormal differentiation of dopaminergic neurons in zebrafish trpm7 mutant larvae impairs development of the motor pattern.Physiology of freezing of gait.Taurine-induced attenuation of MPP+ neurotoxicity in vitro: a possible role for the GABA(A) subclass of GABA receptors.Protection from MPTP-induced neurotoxicity in differentiating mouse N2a neuroblastoma cells.Ablative surgery and deep brain stimulation for Parkinson's disease.A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease.Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.Epidemiology of health and safety risks in agriculture and related industries. Practical applications for rural physicians.Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease modelVisual evoked potentials in parkinsonism and dopamine blockade reveal a stimulus-dependent dopamine function in humans.Ganzfeld electroretinographic findings in parkinsonism: untreated patients and the effect of levodopa intravenous infusion.Low lumbar CSF levels of homovanillic acid and 5-hydroxyindoleacetic acid in multiple system atrophy with autonomic failureImportance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineAnimal models of tremor.Alterations of nocturnal activity in rats following subchronic oral administration of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carbolineTRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP(+).
P2860
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P2860
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@en
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@nl
type
label
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@en
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@nl
prefLabel
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@en
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@nl
P2093
P2860
P921
P356
P1476
A primate model of parkinsonis ...... yl-1,2,3,6-tetrahydropyridine.
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.14.4546
P407
P577
1983-07-01T00:00:00Z