Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.
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Characterization of expression of glycan ligands for Siglec-F in normal mouse lungsGalactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissueMice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammationIL-33 enhances Siglec-8 mediated apoptosis of human eosinophilsDevelopmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expressionProfile of anti-IL-5 mAb mepolizumab in the treatment of severe refractory asthma and hypereosinophilic diseasesNovel Therapies for Eosinophilic DisordersPathogenesis and classification of eosinophil disorders: a review of recent developments in the fieldInterleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders: evidence and unmet needsTherapeutic interventions in severe asthmaMechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activationEngagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancerPolymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma.Whole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation.Mast cell function: a new vision of an old cell.Tyrosine Kinase Inhibitors and Therapeutic Antibodies in Advanced Eosinophilic Disorders and Systemic Mastocytosis.Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation.Non-invasive optical imaging of eosinophilia during the course of an experimental allergic airways disease model and in response to therapy.Potential targeting of siglecs, mast cell inhibitory receptors, in interstitial cystitis.Role of siglecs and related glycan-binding proteins in immune responses and immunoregulationEosinophils: changing perspectives in health and disease.Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-EBiologic therapies targeting eosinophils: current status and future prospects.PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.Allergic Lung Inflammation Reduces Tissue Invasion and Enhances Survival from Pulmonary Pneumococcal Infection in Mice, Which Correlates with Increased Expression of Transforming Growth Factor β1 and SiglecF(low) Alveolar Macrophages.Expression and preliminary functional analysis of Siglec-F on mouse macrophages.Siglec-H protects from virus-triggered severe systemic autoimmunity.Biomarkers of eosinophil involvement in allergic and eosinophilic diseases: review of phenotypic and serum markers including a novel assay to quantify levels of soluble Siglec-8Role of Interleukin-17A on the Chemotactic Responses to CCL7 in a Murine Allergic Rhinitis Model.Effect of anti-siglec-f antibody and reactive oxygen species blocking on histamine release in urinary bladder of ovalbumin-treated mice.The transcriptional profile of coronary arteritis in Kawasaki diseaseRedefining Myeloid Cell Subsets in Murine SpleenSiglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions.Novel targeted therapies for eosinophilic disordersImmortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication."Siglec"ting the allergic response for therapeutic targeting.Glycosylation and other PTMs alterations in neurodegenerative diseases: Current status and future role in neurotrauma.Microbiota and dietary interactions: an update to the hygiene hypothesis?Siglec-8 and Siglec-F, the new therapeutic targets in asthma.Novel identified receptors on mast cells.
P2860
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P2860
Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@en
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@nl
type
label
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@en
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@nl
prefLabel
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@en
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@nl
P2860
P1476
Siglec-8 on human eosinophils ...... related inhibitory receptors.
@en
P2093
B S Bochner
P2860
P304
P356
10.1111/J.1365-2222.2008.03173.X
P577
2009-03-01T00:00:00Z