Targeting of the protein interaction site between FAK and IGF-1R.
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FAK and paxillin, two potential targets in pancreatic cancerMultifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscleInhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivoDOT2: Macromolecular docking with improved biophysical models.FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cellsFocal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.Thioredoxin reductase linked to cytoskeleton by focal adhesion kinase reverses actin S-nitrosylation and restores neutrophil β(2) integrin functionDisruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors.An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABA(B) receptor.Nitric-oxide synthase-2 linkage to focal adhesion kinase in neutrophils influences enzyme activity and β2 integrin functionDual targeting of the insulin-like growth factor and collateral pathways in cancer: combating drug resistance.Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions
P2860
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P2860
Targeting of the protein interaction site between FAK and IGF-1R.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Targeting of the protein interaction site between FAK and IGF-1R.
@en
Targeting of the protein interaction site between FAK and IGF-1R.
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type
label
Targeting of the protein interaction site between FAK and IGF-1R.
@en
Targeting of the protein interaction site between FAK and IGF-1R.
@nl
prefLabel
Targeting of the protein interaction site between FAK and IGF-1R.
@en
Targeting of the protein interaction site between FAK and IGF-1R.
@nl
P2093
P2860
P1476
Targeting of the protein interaction site between FAK and IGF-1R.
@en
P2093
Andrew Magis
David Ostrov
Deniz Ucar
Donghang Zheng
Elena Kurenova
Steven N Hochwald
Vita Golubovskaya
William G Cance
P2860
P304
P356
10.1016/J.BBRC.2009.07.156
P407
P577
2009-08-05T00:00:00Z