The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
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First Line of Defense: Innate Cell-Mediated Control of Pulmonary AspergillosisHistoplasma capsulatum, lung infection and immunityDendritic cells in antifungal immunity and vaccine designDendritic cell interactions with Histoplasma and ParacoccidioidesAdaptive immunity to fungiImmunoregulation in Fungal DiseasesThe role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsisTLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis.Regulation of innate responses during pre-patent schistosome infection provides an immune environment permissive for parasite development.Pulmonary infection with an interferon-gamma-producing Cryptococcus neoformans strain results in classical macrophage activation and protection.Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes.Antigen-presenting dendritic cells rescue CD4-depleted CCR2-/- mice from lethal Histoplasma capsulatum infection.CCR5 dictates the equilibrium of proinflammatory IL-17+ and regulatory Foxp3+ T cells in fungal infection.Metallomic analysis of macrophages infected with Histoplasma capsulatum reveals a fundamental role for zinc in host defenses.Genetic control of immune cell types in fungal disease.CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue.Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair biasIL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.Type II cytokines impair host defense against an intracellular fungal pathogen by amplifying macrophage generation of IL-33.Adaptive immunity to fungi.MyD88-dependent signaling drives host survival and early cytokine production during Histoplasma capsulatum infection.Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity.The role of cytokines and chemokines in Histoplasma capsulatum infection.Mononuclear phagocyte-mediated antifungal immunity: the role of chemotactic receptors and ligands.Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice.Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung.CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension.Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis.Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatumEosinophils subvert host resistance to an intracellular pathogen by instigating non-protective IL-4 in CCR2-/- mice.Innate antifungal immunity: the key role of phagocytes.Innate and adaptive antifungal immune responses: partners on an equal footing.Protective immune responses to fungal infections.Role of dendritic cell-pathogen interactions in the immune response to pulmonary cryptococcal infection.Monocyte-mediated defense against bacteria, fungi, and parasites.Postbiotic Modulation of Retinoic Acid Imprinted Mucosal-like Dendritic Cells by Probiotic Lactobacillus reuteri 17938 In Vitro.Fungi subvert vaccine T cell priming at the respiratory mucosa by preventing chemokine-induced influx of inflammatory monocytes.Immune-Response Patterns and Next Generation Sequencing Diagnostics for the Detection of Mycoses in Patients with Septic Shock-Results of a Combined Clinical and Experimental Investigation.IL-4 Induces Metallothionein 3- and SLC30A4-Dependent Increase in Intracellular Zn(2+) that Promotes Pathogen Persistence in Macrophages.
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The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 July 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@en
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@nl
type
label
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@en
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@nl
prefLabel
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@en
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@nl
P2860
P356
P1476
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
@en
P2093
George S Deepe
Wendy A Szymczak
P2860
P304
P356
10.4049/JIMMUNOL.0901316
P407
P577
2009-07-08T00:00:00Z