Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective.
about
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by meninMLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencingThe role of epigenetics in resistance to Cisplatin chemotherapy in lung cancerIdentification of somatic mutations in parathyroid tumors using whole-exome sequencingMolecular markers of paragangliomas/pheochromocytomasThe menin tumor suppressor protein is phosphorylated in response to DNA damagePancreatic neuroendocrine tumors in glucagon receptor-deficient mice.MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.Impaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1).Loss of MEN1 activates DNMT1 implicating DNA hypermethylation as a driver of MEN1 tumorigenesis.Epigenetic aspects on therapy development for gastroenteropancreatic neuroendocrine tumors.Genetic aspects of adrenocortical tumours and hyperplasias.Everolimus for the treatment of pancreatic neuroendocrine tumors.Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases.Menin Plays a Critical Role in the Regulation of the Antigen-Specific CD8+ T Cell Response upon Listeria Infection.Menin and JunD regulate gastrin gene expression through proximal DNA elements.Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells.Epigenetic regulation by the menin pathway.Complete genomic landscape of a recurring sporadic parathyroid carcinoma.BRD4 inhibitor IBET upregulates p27kip/cip protein stability in neuroendocrine tumor cells.Downregulation of tumor suppressor menin by miR-421 promotes proliferation and migration of neuroblastoma.
P2860
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P2860
Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on December 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@en
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@nl
type
label
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@en
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@nl
prefLabel
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@en
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@nl
P2860
P1476
Menin, histone h3 methyltransf ...... ent knowledge and perspective.
@en
P2093
Xianxin Hua
Xinjiang Wu
P2860
P304
P356
10.2174/156652408786733702
P577
2008-12-01T00:00:00Z