Synovial perlecan is required for osteophyte formation in knee osteoarthritis. - Wikidata - awgldk - TriplyDB

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

http://www.wikidata.org/entity/Q37349431

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Proteoglycan form and function: A comprehensive nomenclature of proteoglycans The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy A current view of perlecan in physiology and pathology: A mosaic of functions.Endorepellin evokes autophagy in endothelial cells Sex-Specific Protection of Osteoarthritis by Deleting Cartilage Acid Protein 1.Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior.Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept.The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix.Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice.Controlling Abnormal Joint Movement Inhibits Response of Osteophyte Formation.Using mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase.Lectin-like oxidized low density lipoprotein receptor 1-deficient mice show resistance to instability-induced osteoarthritis.Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in patients with early-stage knee osteoarthritis Subchondral mesenchymal stem cells from osteoarthritic knees display high osteogenic differentiation capacity through microRNA-29a regulation of HDAC4.Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression.Dkk-1-Mediated Inhibition of Wnt Signaling in Bone Ameliorates Osteoarthritis in Mice

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Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

http://www.wikidata.org/entity/Q37349431

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 20 January 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@en

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

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type

label

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@en

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@nl

prefLabel

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@en

Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@nl

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J.MATBIO.2013.01.004

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Synovial perlecan is required for osteophyte formation in knee osteoarthritis.

@en

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Eri Arikawa-Hirasawa

http://www.w3.org/2001/XMLSchema#string

Haruka Kaneko

http://www.w3.org/2001/XMLSchema#string

Hisashi Kurosawa

http://www.w3.org/2001/XMLSchema#string

Ippei Futami

http://www.w3.org/2001/XMLSchema#string

Kazuo Kaneko

http://www.w3.org/2001/XMLSchema#string

Keisuke Kosaki

http://www.w3.org/2001/XMLSchema#string

Muneaki Ishijima

http://www.w3.org/2001/XMLSchema#string

Naoki Tomikawa-Ichikawa

http://www.w3.org/2001/XMLSchema#string

Ryo Sadatsuki

http://www.w3.org/2001/XMLSchema#string

Yoshihiko Yamada

http://www.w3.org/2001/XMLSchema#string

P2860

Perlecan maintains the integrity of cartilage and some basement membranes

Perlecan is essential for cartilage and cephalic development

Perlecan: a gem of a proteoglycan

The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans

Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation

Treatment with insulin-like growth factor-1 increases chondrogenesis by periosteum in vitro.

Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation.

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition.

Isolation and characterization of multipotential mesenchymal cells from the mouse synovium.

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178-187

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scholarly article

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10.1016/J.MATBIO.2013.01.004

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3-4

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32

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2013-01-20T00:00:00Z

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