Murine Fig4 is dispensable for muscle development but required for muscle function. - Wikidata - awgldk - TriplyDB

Murine Fig4 is dispensable for muscle development but required for muscle function.

Murine Fig4 is dispensable for muscle development but required for muscle function.

http://www.wikidata.org/entity/Q37351972

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PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation.FIG4 regulates lysosome membrane homeostasis independent of phosphatase function.Protective Role of the Lipid Phosphatase Fig4 in the Adult Nervous System.

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Murine Fig4 is dispensable for muscle development but required for muscle function.

http://www.wikidata.org/entity/Q37351972

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on September 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Murine Fig4 is dispensable for muscle development but required for muscle function.

@en

Murine Fig4 is dispensable for muscle development but required for muscle function.

@nl

type

label

Murine Fig4 is dispensable for muscle development but required for muscle function.

@en

Murine Fig4 is dispensable for muscle development but required for muscle function.

@nl

prefLabel

Murine Fig4 is dispensable for muscle development but required for muscle function.

@en

Murine Fig4 is dispensable for muscle development but required for muscle function.

@nl

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Skeletal Muscle

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Murine Fig4 is dispensable for muscle development but required for muscle function.

@en

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Desmond Wilson

http://www.w3.org/2001/XMLSchema#string

James J Dowling

http://www.w3.org/2001/XMLSchema#string

Linda Groom

http://www.w3.org/2001/XMLSchema#string

Michyla Bowerson

http://www.w3.org/2001/XMLSchema#string

Miriam H Meisler

http://www.w3.org/2001/XMLSchema#string

Robert T Dirksen

http://www.w3.org/2001/XMLSchema#string

Xingli Li

http://www.w3.org/2001/XMLSchema#string

P2860

A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.

Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder

The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover

Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy

Phosphoinositides in cell regulation and membrane dynamics

Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

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21

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scholarly article

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10.1186/2044-5040-3-21

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1

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2013-09-01T00:00:00Z

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3844516

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