Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons. - Wikidata - awgldk - TriplyDB

Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons.

Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons.

http://www.wikidata.org/entity/Q37352456

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Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.Prenatal stress and inhibitory neuron systems: implications for neuropsychiatric disorders Decision making during interneuron migration in the developing cerebral cortex OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum Possible functional links among brain- and skull-related genes selected in modern humans Direct generation of functional dopaminergic neurons from mouse and human fibroblasts A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome.Broad integration of expression maps and co-expression networks compassing novel gene functions in the brain.Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus.Ascl1 promotes tangential migration and confines migratory routes by induction of Ephb2 in the telencephalon.Arx is required for specification of the zona incerta and reticular nucleus of the thalamus.Role for TGF-beta superfamily signaling in telencephalic GABAergic neuron development.Mutations in ARX Result in Several Defects Involving GABAergic Neurons.Epilepsy genetics--past, present, and future Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq.NPAS1 represses the generation of specific subtypes of cortical interneurons Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position.Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c.Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders Genomic perspectives of transcriptional regulation in forebrain development.Increased behavioral responses to ethanol in Lmo3 knockout mice Differential effects of a polyalanine tract expansion in Arx on neural development and gene expression.Developmental interneuron subtype deficits after targeted loss of Arx Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons.Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling.Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex A high-resolution enhancer atlas of the developing telencephalon.Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development Interneuron development and epilepsy: early genetic defects cause long-term consequences in seizures and susceptibility.Arx polyalanine expansion in mice leads to reduced pancreatic α-cell specification and increased α-cell death.The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein.Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain.Involvement of cortical fast-spiking parvalbumin-positive basket cells in epilepsy.Integrative mechanisms of oriented neuronal migration in the developing brain.

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Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons.

http://www.wikidata.org/entity/Q37352456

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artigo científico

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bilimsel makale

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scientific article published on October 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@en

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@nl

type

label

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@en

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@nl

prefLabel

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@en

Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

@nl

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JNEUROSCI.1283-08.2008

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Journal of Neuroscience

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Arx is a direct target of Dlx2 ...... ion of GABAergic interneurons.

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Ahmed Mansouri

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Dario Bonanomi

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John L R Rubenstein

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Kazuaki Yoshikawa

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Mario Maira

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Valentina Raimondi

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P2860

Highly conserved non-coding sequences are associated with vertebrate development

Analysis of four DLX homeobox genes in autistic probands

Ultraconserved Elements in the Human Genome

Developmental functions of the Distal-less/Dlx homeobox genes

Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1

ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation

Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain

A new paradigm for West syndrome based on molecular and cell biology

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10674-10686

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scholarly article

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10.1523/JNEUROSCI.1283-08.2008

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42

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Patrick Collombat

Flavia Valtorta

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2008-10-01T00:00:00Z

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23387246

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18923043

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3844830

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