Safety and immunologic effects of IL-15 administration in nonhuman primates. - Wikidata - awgldk - TriplyDB

Safety and immunologic effects of IL-15 administration in nonhuman primates.

Safety and immunologic effects of IL-15 administration in nonhuman primates.

http://www.wikidata.org/entity/Q37352474

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Interleukin-15 biology and its therapeutic implications in cancer The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use T cell receptor gene therapy for cancer NK Cells in HIV Disease Immunotherapy of Childhood Sarcomas NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity in Cancer Immunotherapy IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells Interleukin-7 and interleukin-15 for cancer Chimeric antigen receptor therapy for cancer Immunology in the clinic review series; focus on cancer: double trouble for tumours: bi-functional and redirected T cells as effective cancer immunotherapies Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques Targeted immunotherapy for acute myeloid leukemia Improving cell-based therapies by nanomodification IL15 and T-cell Stemness in T-cell-Based Cancer Immunotherapy The shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapy Cell delivery of therapeutic nanoparticles Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells T cell receptor (TCR) gene therapy to treat melanoma: lessons from clinical and preclinical studies.Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in vivo cytokine administration: implications for clinical therapy.Redirecting the immune response: role of adoptive T cell therapy.Adoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation.Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy.IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy A non-human primate model for analysis of safety, persistence, and function of adoptively transferred T cells.GD2-targeted immunotherapy and radioimmunotherapy Characterization and favorable in vivo properties of heterodimeric soluble IL-15·IL-15Rα cytokine compared to IL-15 monomer.IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo.Adoptive T cell therapy of cancer.Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques.Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.Imaging and quantifying solute transport across periosteum: implications for muscle-bone crosstalk.Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice.Specific pathogen-free status alters immunophenotype in rhesus macaques: implications for the study of simian immunodeficiency virus.Neuroblastoma: developmental biology, cancer genomics and immunotherapy.Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood Increased serum soluble IL-15Rα levels in T-cell large granular lymphocyte leukemia

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P2860

Safety and immunologic effects of IL-15 administration in nonhuman primates.

http://www.wikidata.org/entity/Q37352474

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 15 July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@en

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@nl

type

label

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@en

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@nl

prefLabel

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@en

Safety and immunologic effects of IL-15 administration in nonhuman primates.

@nl

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BLOOD-2008-12-189266

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Safety and immunologic effects of IL-15 administration in nonhuman primates.

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P2093

Carole Elliott

http://www.w3.org/2001/XMLSchema#string

Carolina Berger

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Michael Berger

http://www.w3.org/2001/XMLSchema#string

Michael C Jensen

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Michael Gough

http://www.w3.org/2001/XMLSchema#string

Robert C Hackman

http://www.w3.org/2001/XMLSchema#string

Stanley R Riddell

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

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Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

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2417-2426

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scholarly article

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10.1182/BLOOD-2008-12-189266

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2009-07-15T00:00:00Z

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19605850

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2746471

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