Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A. - Wikidata - awgldk - TriplyDB

Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A.

Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A.

http://www.wikidata.org/entity/Q37352993

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The concept of idiotypic vaccination against factor VIII inhibitors in haemophilia A.Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.Tolerance to factor VIII inhibitors in hemophilia A patients: a French twist.ITI choice for the optimal management of inhibitor patients - from a clinical and pharmacoeconomic perspective.High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors.Bortezomib delays the onset of factor VIII inhibitors in experimental hemophilia A, but fails to eliminate established anti-factor VIII IgG-producing cells.Successful immune tolerance induction by FVIII in hemophilia A patients with inhibitor may occur without deletion of FVIII-specific T cells.Disappearance of factor VIII autoantibodies preceding autoimmune haemolytic anaemia.Understanding FVIII/VWF complex--report from a symposium of XXIX WFH meeting 2010.

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Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A.

http://www.wikidata.org/entity/Q37352993

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on March 1996

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

@en

Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

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type

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Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

@en

Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

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prefLabel

Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

@en

Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

@nl

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Journal of Clinical Investigation

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Neutralizing antiidiotypic ant ...... in patients with hemophilia A.

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Desqueper B

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Gilles JG

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Lenk H

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Saint-Remy JM

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Vermylen J

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P2860

Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies.

Recovery from anti-VIII:C (antihemophilic factor) autoimmune disease is dependent on generation of antiidiotypes against anti-VIII:C autoantibodies.

Regulation of immune response by autogenous antibody against receptor.

Anti-idiotypic suppression of autoantibodies to factor VIII (antihaemophilic factor) by high-dose intravenous gammaglobulin.

Induction of tolerance to factor VIII in a child with a high-titer inhibitor: in vitro and in vivo observations.

Anti-factor VIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction.

Disappearance of factor VIII:C antibodies in patients with haemophilia A upon frequent administration of factor VIII in intermediate or low dose.

Incidence of inhibitors in patients with severe and moderate hemophilia A treated with factor VIII concentrates.

The natural history of factor VIII:C inhibitors in patients with hemophilia A: a national cooperative study. II. Observations on the initial development of factor VIII:C inhibitors.

Anti-idiotypes against autoantibodies and alloantibodies to VIII:C (anti-haemophilic factor) are present in therapeutic polyspecific normal immunoglobulins.

P304

1382-1388

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scholarly article

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10.1172/JCI118558

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6

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97

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1996-03-01T00:00:00Z

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14582428

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8617869

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Coagulation factor VIII

P932

507196

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