Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia.
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Thrombopoietin.Filgrastim improves survival in lethally irradiated nonhuman primatesIncreased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation.Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models.Preliminary nonclinical toxicity, pharmacokinetics, and pharmacodynamics of ALXN4100TPO, a thrombopoietin receptor agonist, in CD2F1 mice.Thrombopoietin Receptor Agonist Mitigates Hematopoietic Radiation Syndrome and Improves Survival after Whole-Body Ionizing Irradiation Followed by Wound TraumaAn anti-apoptotic peptide improves survival in lethal total body irradiation.Civilian nuclear incidents: An overview of historical, medical, and scientific aspectsAcute radiation syndrome (ARS) - treatment of the reduced host defense.Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesisMyeloid growth factors in oncology.Radiation injury after a nuclear detonation: medical consequences and the need for scarce resources allocation.Establishing a murine model of the hematopoietic syndrome of the acute radiation syndromeSurvival efficacy of the PEGylated G-CSFs Maxy-G34 and neulasta in a mouse model of lethal H-ARS, and residual bone marrow damage in treated survivors.History and development of radiation-protective agents.Radiation victim management and the haematologist in the future: time to revisit therapeutic guidelines?The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis.Granulocyte colony-stimulating factor in the treatment of acute radiation syndrome: a concise review.Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review.Nonhuman primates as models for the discovery and development of radiation countermeasures.Regulation of polymorphonuclear cell activation by thrombopoietin.Combined Therapy of Pegylated G-CSF and Alxn4100TPO Improves Survival and Mitigates Acute Radiation Syndrome after Whole-Body Ionizing Irradiation alone and Followed by Wound Trauma.Platelet-like particle production from cultured human megakaryocytic cell line.Role for C-MPL and its ligand thrombopoietin in early hematopoiesis.In vitro and in vivo expansion of stem cell populations.Cytokines in hematopoiesis.An oral HemokineTM, α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo.
P2860
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P2860
Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Combined administration of rec ...... iation-induced marrow aplasia.
@en
Combined administration of rec ...... iation-induced marrow aplasia.
@nl
type
label
Combined administration of rec ...... iation-induced marrow aplasia.
@en
Combined administration of rec ...... iation-induced marrow aplasia.
@nl
prefLabel
Combined administration of rec ...... iation-induced marrow aplasia.
@en
Combined administration of rec ...... iation-induced marrow aplasia.
@nl
P2093
P2860
P356
P1476
Combined administration of rec ...... iation-induced marrow aplasia.
@en
P2093
P2860
P304
P356
10.1172/JCI118652
P407
P577
1996-05-01T00:00:00Z