Tying synaptonemal complex initiation to the formation and programmed repair of DNA double-strand breaks.
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Synthesis-dependent strand annealing in meiosisSUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiaeRepair of strand breaks by homologous recombinationSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsIpl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosisSustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast.Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosisAnalysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae.Differential association of the conserved SUMO ligase Zip3 with meiotic double-strand break sites reveals regional variations in the outcome of meiotic recombination.Pds1p is required for meiotic recombination and prophase I progression in Saccharomyces cerevisiae.Recombination, Pairing, and Synapsis of Homologs during MeiosisExposure to the widely used herbicide atrazine results in deregulation of global tissue-specific RNA transcription in the third generation and is associated with a global decrease of histone trimethylation in miceZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing overHORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytesGradual implementation of the meiotic recombination program via checkpoint pathways controlled by global DSB levelsBioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labelingMeiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.Zip4/Spo22 is required for class I CO formation but not for synapsis completion in Arabidopsis thaliana.Excess single-stranded DNA inhibits meiotic double-strand break repair.CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis.Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosisThe pch2Delta mutation in baker's yeast alters meiotic crossover levels and confers a defect in crossover interference.Temporal characterization of homology-independent centromere coupling in meiotic prophase.Changing partners: moving from non-homologous to homologous centromere pairing in meiosis.Meiotic cohesin promotes pairing of nonhomologous centromeres in early meiotic prophaseSordaria, a model system to uncover links between meiotic pairing and recombination.Homologous chromosome interactions in meiosis: diversity amidst conservation.Topoisomerase II mediates meiotic crossover interferenceThe meiotic checkpoint network: step-by-step through meiotic prophaseMek1 kinase governs outcomes of meiotic recombination and the checkpoint response.Does crossover interference count in Saccharomyces cerevisiae?Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII.Meiotic recombination in Drosophila females depends on chromosome continuity between genetically defined boundaries.FindFoci: a focus detection algorithm with automated parameter training that closely matches human assignments, reduces human inconsistencies and increases speed of analysisHigh throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activityChemical inactivation of cdc7 kinase in budding yeast results in a reversible arrest that allows efficient cell synchronization prior to meiotic recombinationMeiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatidsReduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM.The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine.Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.
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Tying synaptonemal complex initiation to the formation and programmed repair of DNA double-strand breaks.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 March 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@en
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@nl
type
label
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@en
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@nl
prefLabel
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@en
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@nl
P2860
P356
P1476
Tying synaptonemal complex ini ...... r of DNA double-strand breaks.
@en
P2093
Kiersten A Henderson
Scott Keeney
P2860
P304
P356
10.1073/PNAS.0400843101
P407
P577
2004-03-18T00:00:00Z