Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. - Wikidata - awgldk - TriplyDB

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

http://www.wikidata.org/entity/Q37359194

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The TOR pathway comes of age Lessons on longevity from budding yeast mTOR is a key modulator of ageing and age-related disease An emerging role for TOR signaling in mammalian tissue and stem cell physiology Aging as an event of proteostasis collapse Replicative and chronological aging in Saccharomyces cerevisiae.mTOR: from growth signal integration to cancer, diabetes and ageing Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond The role of the ribosome in the regulation of longevity and lifespan extension Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae The many ways to age for a single yeast cell Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans The circadian clock coordinates ribosome biogenesis Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast.A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability.A mutant plasma membrane protein is stabilized upon loss of Yvh1, a novel ribosome assembly factor.Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.Termination of isoform-selective Vps21/Rab5 signaling at endolysosomal organelles by Msb3/Gyp3.Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disorders Rapalogs and mTOR inhibitors as anti-aging therapeutics Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans Suppression of replicative senescence by rapamycin in rodent embryonic cells Elevated histone expression promotes life span extension Midlife gene expressions identify modulators of aging through dietary interventions.Calorie restriction effects on silencing and recombination at the yeast rDNA.Calorie restriction reduces rDNA recombination independently of rDNA silencing.The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1 Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.Discovery of chemical modulators of a conserved translational control pathway by parallel screening in yeast.Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae Growth and aging: a common molecular mechanism.Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response Intertissue control of the nucleolus via a myokine-dependent longevity pathway.

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Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

http://www.wikidata.org/entity/Q37359194

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@en

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@nl

type

label

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@en

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@nl

prefLabel

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@en

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

@nl

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P356

J.CELL.2008.02.037

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P1476

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4

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Bie N Tchao

http://www.w3.org/2001/XMLSchema#string

Di Hu

http://www.w3.org/2001/XMLSchema#string

Diana N Pak

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Elijah D Johnston

http://www.w3.org/2001/XMLSchema#string

Emily O Kerr

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Jonathan A Oakes

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Kristan K Steffen

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Lindsay A Fox

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Mitsuhiro Tsuchiya

http://www.w3.org/2001/XMLSchema#string

Nick Dang

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P2860

Sir2-independent life span extension by calorie restriction in yeast

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

Extension of chronological life span in yeast by decreased TOR pathway signaling

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

Genes determining yeast replicative life span in a long-lived genetic background.

Elimination of replication block protein Fob1 extends the life span of yeast mother cells.

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292-302

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10.1016/J.CELL.2008.02.037

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2

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Brian K Kennedy

Matt Kaeberlein

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2008-04-01T00:00:00Z

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5429898

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