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Exome sequencing identifies DLG1 as a novel gene for potential susceptibility to Crohn's disease in a Chinese family studyCanalization and control in automata networks: body segmentation in Drosophila melanogasterFinding the missing heritability of complex diseasesReplication in Genome-Wide Association StudiesRobustness: mechanisms and consequencesGenetics of asthma: an introduction for the clinicianMolecular mechanisms of robustness in plantsRole of pleiotropy in the evolution of a cryptic developmental variation in Caenorhabditis elegansAltered gene synchrony suggests a combined hormone-mediated dysregulated state in major depressionPhenotypic plasticity of the Drosophila transcriptomeDeep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasisApproaching motor and language deficits in autism from below: a biolinguistic perspectiveUniversal Grammar and Biological Variation: An EvoDevo Agenda for Comparative BiolinguisticsNetwork biology concepts in complex disease comorbiditiesGenetic Effects on the Correlation Structure of CVD Risk Factors: Exome-Wide Data From a Ghanaian Population.Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations.Geographical genomics of human leukocyte gene expression variation in southern MoroccoTransient genotype-by-environment interactions following environmental shock provide a source of expression variation for essential genesGenetic association of objective sleep phenotypes with a functional polymorphism in the neuropeptide S receptor gene.SNPs in the FCER1A gene region show no association with allergic rhinitis in a Han Chinese population.Data mining and the evolution of biological complexityWhat causes alopecia areata?A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects.Variance of gene expression identifies altered network constraints in neurological disease.Genotype-by-diet interactions drive metabolic phenotype variation in Drosophila melanogaster.Distinct genetic architectures for male and female inflorescence traits of maize.Improving disease gene prioritization using the semantic similarity of Gene Ontology termsSynthetic lethality: general principles, utility and detection using genetic screens in human cellsHeterogeneity of genetic modifiers ensures normal cardiac developmentArtificial neural networks modeling gene-environment interaction.A knowledge-based method for association studies on complex diseasesDirectional selection causes decanalization in a group I ribozyme.Lessons from model organisms: phenotypic robustness and missing heritability in complex disease.Progress and promise of genome-wide association studies for human complex trait geneticsComplex systems analysis of bladder cancer susceptibility reveals a role for decarboxylase activity in two genome-wide association studiesGenome-wide association study of sleep in Drosophila melanogasterHigher-order genetic interactions and their contribution to complex traits.Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan.Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease.Temperature stress mediates decanalization and dominance of gene expression in Drosophila melanogaster.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Decanalization and the origin of complex disease.
@en
Decanalization and the origin of complex disease.
@nl
type
label
Decanalization and the origin of complex disease.
@en
Decanalization and the origin of complex disease.
@nl
prefLabel
Decanalization and the origin of complex disease.
@en
Decanalization and the origin of complex disease.
@nl
P356
P1476
Decanalization and the origin of complex disease.
@en
P2093
Greg Gibson
P2888
P304
P356
10.1038/NRG2502
P577
2009-01-02T00:00:00Z
P5875
P6179
1005380080