In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
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Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterificationMetabolism of very-low-density lipoprotein and low-density lipoprotein containing apolipoprotein C-III and not other small apolipoproteinsANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipaseA decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient miceDefective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient miceAPOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal CanadiansAspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet.Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables.Constitutive inhibition of plasma CETP by apolipoprotein C1 is blunted in dyslipidemic patients with coronary artery disease.Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice.Corticosterone regulation of ovarian follicular development is dependent on the energy status of laying hens.Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic miceApoE and ApoC-I polymorphisms: association of genotype with cardiovascular disease phenotype in African AmericansApolipoprotein CI is a physiological regulator of cholesteryl ester transfer protein activity in human plasma but not in rabbit plasma.Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1.The use of network analyses for elucidating mechanisms in cardiovascular disease.The potential of cholesteryl ester transfer protein as a therapeutic target.Apolipoprotein CI overexpression is not a relevant strategy to block cholesteryl ester transfer protein (CETP) activity in CETP transgenic mice.The apolipoprotein C-I content of very-low-density lipoproteins is associated with fasting triglycerides, postprandial lipemia, and carotid atherosclerosisReversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.The interaction of human apolipoprotein C-I with sub-micellar phospholipid.Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/ApoCI-knocked out mice.Plasma kinetics of VLDL and HDL apoC-I in normolipidemic and hypertriglyceridemic subjects.Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion.Overexpression of apoC-I in apoE-null mice: severe hypertriglyceridemia due to inhibition of hepatic lipase.Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance.Apolipoprotein C-I plays a role in the pathogenesis of glomerulosclerosis.Global proteomic profiling reveals altered proteomic signature in schizophrenia serum.Human apolipoprotein C-I expression in mice impairs learning and memory functions.Effects of apoC1 genotypes on the hormonal levels, metabolic profile and PAF-AH activity in Chinese women with polycystic ovary syndrome.Minireview
P2860
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P2860
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
In the absence of the low dens ...... ted protein-sensitive pathway.
@en
In the absence of the low dens ...... ted protein-sensitive pathway.
@nl
type
label
In the absence of the low dens ...... ted protein-sensitive pathway.
@en
In the absence of the low dens ...... ted protein-sensitive pathway.
@nl
prefLabel
In the absence of the low dens ...... ted protein-sensitive pathway.
@en
In the absence of the low dens ...... ted protein-sensitive pathway.
@nl
P2093
P2860
P356
P1476
In the absence of the low dens ...... ted protein-sensitive pathway.
@en
P2093
Dahlmans VE
Havekes LM
van Dijk KW
van Gorp PJ
P2860
P304
P356
10.1172/JCI119036
P407
P577
1996-11-01T00:00:00Z