Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
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The role of transporters in toxicity and diseaseMembrane transporters in drug developmentDimerization of ABCG2 analysed by bimolecular fluorescence complementation.Interaction of mammary bovine ABCG2 with AFB1 and its metabolites and regulation by PCB 126 in a MDCKII in vitro model.Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).Fungicide prochloraz and environmental pollutant dioxin induce the ABCG2 transporter in bovine mammary epithelial cells by the arylhydrocarbon receptor signaling pathway.Pharmacological correction of misfolding of ABC proteins.In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs.The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins.Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites.The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows.Efflux and uptake transporters involved in the disposition of bazedoxifene.Novel in vitro systems for prediction of veterinary drug residues in ovine milk and dairy products.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model.The dual-targeted HER1/HER2 tyrosine kinase inhibitor lapatinib strongly potentiates the cardiac myocyte-damaging effects of doxorubicin.Reply to the comment of Ana I. Alvarez and Gracia Merino regarding "Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model" by Wassermann et al. 2013.A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions.Computational classification models for predicting the interaction of drugs with P-glycoprotein and breast cancer resistance protein.Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.
P2860
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P2860
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@en
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@nl
type
label
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@en
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@nl
prefLabel
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@en
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@nl
P2093
P1476
Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays.
@en
P2093
Agnes Telbisz
Balázs Sarkadi
Csilla Hegedus
Gergely Szakács
László Homolya
Márton Jani
Tamás I Orbán
P356
10.1016/J.ADDR.2008.09.007
P407
P577
2008-12-24T00:00:00Z