Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity.
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Structure–function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097Structural analysis and biological activities of BXL0124, a gemini analog of vitamin DVitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysisInhibition of the transition of ductal carcinoma in situ to invasive ductal carcinoma by a Gemini vitamin D analog.Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activityInteractions between vitamin D and IGF-I: from physiology to clinical practice.Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer.Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.A novel Gemini vitamin D analog represses the expression of a stem cell marker CD44 in breast cancer20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up studyHES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: importance of mammary CYP27B1 for treatment and prevention.Vitamin d: are we ready to supplement for breast cancer prevention and treatment?Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.Oral administration of a gemini vitamin D analog, a synthetic triterpenoid and the combination prevents mammary tumorigenesis driven by ErbB2 overexpression.The future of vitamin D analogs.Recent developments of 19-nor-1,25-dihydroxyvitamin D3 analogues.Chaperone properties of pdia3 participate in rapid membrane actions of 1α,25-dihydroxyvitamin d3Gemini vitamin D analog suppresses ErbB2-positive mammary tumor growth via inhibition of ErbB2/AKT/ERK signaling.Calcitriol derivatives with two different side chains at C-20. V. Potent inhibitors of mammary carcinogenesis and inducers of leukemia differentiation
P2860
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P2860
Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@en
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@nl
type
label
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@en
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@nl
prefLabel
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@en
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@nl
P2093
P2860
P1476
Gemini vitamin D analogues inh ...... ithout hypercalcemic toxicity.
@en
P2093
Allan H Conney
Brian Buckley
Hong Jin Lee
Hubert Maehr
Luciano Adorini
Milan Uskokovic
Nadi Atalla
Nanjoo Suh
P2860
P304
P356
10.1158/1940-6207.CAPR-08-0084
P577
2008-11-01T00:00:00Z