Plasma lipoproteins: genetic influences and clinical implications.
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Three-dimensional cryoEM reconstruction of native LDL particles to 16Å resolution at physiological body temperatureHuman genetics and genomics a decade after the release of the draft sequence of the human genomeLow-density lipoprotein cholesterol, apolipoprotein B, and risk of coronary heart disease: from familial hyperlipidemia to genomicsTranscriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery diseasePopulation genomics reveal recent speciation and rapid evolutionary adaptation in polar bearsPlanning for translational research in genomicsExcess of rare variants in genes identified by genome-wide association study of hypertriglyceridemiaAdipose tissue dysfunction and hypertriglyceridemia: mechanisms and management.Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.Tgif1 represses apolipoprotein gene expression in liver.ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1.Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans.Nutrigenomics in cardiovascular medicine.Lipoprotein (a) in type 2 diabetes mellitus: Relation to LDL:HDL ratio and glycemic control.Brain Control of Plasma Cholesterol Involves Polysialic Acid Molecules in the Hypothalamus.APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal CanadiansQuantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism.Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women.A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.Genome-wide linkage scan to identify loci associated with type 2 diabetes and blood lipid phenotypes in the Sikh Diabetes Study.Genetic causes of high and low serum HDL-cholesterol.A differential network approach to exploring differences between biological states: an application to prediabetesUnivariate and bivariate linkage analysis identifies pleiotropic loci underlying lipid levels and type 2 diabetes risk.Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection.Association of genetic loci with blood lipids in the Chinese populationModified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease.The empirical power of rare variant association methods: results from sanger sequencing in 1,998 individuals.Sortilin: an unusual suspect in cholesterol metabolism: from GWAS identification to in vivo biochemical analyses, sortilin has been identified as a novel mediator of human lipoprotein metabolism.Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for managementTransient infantile hypertriglyceridemia, fatty liver, and hepatic fibrosis caused by mutated GPD1, encoding glycerol-3-phosphate dehydrogenase 1The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management.Hepatic trans-Golgi action coordinated by the GTPase ARFRP1 is crucial for lipoprotein lipidation and assembly.APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family.Genetic determinants of plasma triglyceridesEffects of genetic variants on lipid parameters and dyslipidemia in a Chinese population.Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and AfricaExtremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular diseaseRare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study.Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression.Genetic architecture of circulating lipid levels
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Plasma lipoproteins: genetic influences and clinical implications.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Plasma lipoproteins: genetic influences and clinical implications.
@en
Plasma lipoproteins: genetic influences and clinical implications.
@nl
type
label
Plasma lipoproteins: genetic influences and clinical implications.
@en
Plasma lipoproteins: genetic influences and clinical implications.
@nl
prefLabel
Plasma lipoproteins: genetic influences and clinical implications.
@en
Plasma lipoproteins: genetic influences and clinical implications.
@nl
P356
P1476
Plasma lipoproteins: genetic influences and clinical implications.
@en
P2888
P304
P356
10.1038/NRG2481
P577
2009-01-13T00:00:00Z