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Pathophysiology of Anemia During the Neonatal Period, Including Anemia of PrematurityDecreased fetal erythropoiesis and hemolysis in Kell hemolytic anemiaEffect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants.Erythropoietic response to endogenous erythropoietin in premature very low birth weight infantsIs there a role for autologous/placental red blood cell transfusions in the anemia of prematurity?Increased fetal plasma and amniotic fluid erythropoietin concentrations: markers of intrauterine hypoxiaThe effect of anticoagulant, storage temperature and dilution on cord blood hematology parameters over time.Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants.A 'bottom-up' approach for endo-PK/PD analysisEvidence of receptor-mediated elimination of erythropoietin by analysis of erythropoietin receptor mRNA expression in bone marrow and erythropoietin clearance during anemia.Change in erythropoietin pharmacokinetics following hematopoietic transplantation.International survey of transfusion practices for extremely premature infants.Red blood cell (RBC) volume can be independently determined in vivo in humans using RBCs labeled at different densities of biotin.Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin.Red blood cell (RBC) survival determined in humans using RBCs labeled at multiple biotin densitiesReceptor-based dosing optimization of erythropoietin in juvenile sheep after phlebotomy.Pharmacokinetic analysis of continuous erythropoietin receptor activator disposition in adult sheep using a target-mediated, physiologic recirculation model and a tracer interaction methodology.A mathematical modeling approach to quantify the role of phlebotomy losses and need for transfusions in neonatal anemia.Accelerated removal of antibody-coated red blood cells from the circulation is accurately tracked by a biotin label.Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease.How fast is too fast? a practice change in umbilical arterial catheter blood sampling using the Iowa Model for Evidence-Based Practice.Long-term outcome of brain structure in premature infants: effects of liberal vs restricted red blood cell transfusions.Pharmacodynamic analysis of stress erythropoiesis: change in erythropoietin receptor pool size following double phlebotomies in sheepNonpharmacological, blood conservation techniques for preventing neonatal anemia--effective and promising strategies for reducing transfusion.Increased erythropoiesis and elevated erythropoietin in infants born to diabetic mothers and in hyperinsulinemic rhesus fetuses.Red cell volume can be accurately determined in sheep using a nonradioactive biotin labelComparison of the Bactec 9240 and BacT/Alert blood culture systems for evaluation of placental cord blood for transfusion in neonates.Red blood cell volume can be independently determined in vitro using sheep and human red blood cells labeled at different densities of biotinPharmacodynamic modeling of the effect of changes in the environment on cellular lifespan and cellular response.Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep.Differential pharmacokinetic analysis of in vivo erythropoietin receptor interaction with erythropoietin and continuous erythropoietin receptor activator in sheepChronic hyperinsulinemia in the fetal rhesus monkey: effects on fetal growth and composition.Hemoglobin AIc in the glucose-intolerant, streptozotocin-treated or pancreatectomized macaque monkey.Placentas in pregnancies complicated by maternal diabetes.Chronic hyperinsulinemia in the fetal rhesus monkey: effects on hepatic enzymes active in lipogenesis and carbohydrate metabolism.Erythropoietin transplacental passage--review of animal studies.Posttransfusion 24-hour recovery and subsequent survival of allogeneic red blood cells in the bloodstream of newborn infants.Changing patterns of red blood cell transfusion in very low birth weight infants.Effects of prolonged hyperinsulinemia on erythropoiesis in fetal sheep.The effect of prolonged intrauterine hyperinsulinemia on iron utilization in fetal sheep.
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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Jack
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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John A Widness
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P106
P1412
P21
P31
P496
0000-0001-6543-5927