Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
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Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies.The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases.Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics.A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues.E46K α-synuclein pathological mutation causes cell-autonomous toxicity without altering protein turnover or aggregation.Molecular Role of Ca2+ and Hard Divalent Metal Cations on Accelerated Fibrillation and Interfibrillar Aggregation of α-Synuclein.Cryo-EM structure of alpha-synuclein fibrilsSecretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured CellsNeurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative StressMembrane binding, internalization, and sorting of alpha-synuclein in the cell
P2860
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P2860
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 October 2016
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Environmental and genetic fact ...... lein aggregation and toxicity.
@en
Environmental and genetic fact ...... lein aggregation and toxicity.
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type
label
Environmental and genetic fact ...... lein aggregation and toxicity.
@en
Environmental and genetic fact ...... lein aggregation and toxicity.
@nl
prefLabel
Environmental and genetic fact ...... lein aggregation and toxicity.
@en
Environmental and genetic fact ...... lein aggregation and toxicity.
@nl
P2093
P2860
P50
P356
P1476
Environmental and genetic fact ...... clein aggregation and toxicity
@en
P2093
Anita Carija
Anna Villar-Piqué
Caterina Masaracchia
Ellen Gerhardt
Enrique Abad Gonzalez
Markus Zweckstetter
Raquel Pinho
Ricardo Sant'Anna
Tomás Lopes da Fonseca
Éva Mónika Szegö
P2860
P304
E6506-E6515
P356
10.1073/PNAS.1606791113
P407
P50
P577
2016-10-05T00:00:00Z