Differential effect of membrane cholesterol removal on mu- and delta-opioid receptors: a parallel comparison of acute and chronic signaling to adenylyl cyclase
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G protein-coupled receptors: what a difference a 'partner' makesDifferential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cellsExploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor.Sarcolemmal cholesterol and caveolin-3 dependence of cardiac function, ischemic tolerance, and opioidergic cardioprotectionA Pluridimensional View of Biased Agonism.Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.Cholesterol regulates micro-opioid receptor-induced beta-arrestin 2 translocation to membrane lipid rafts.Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol.Desensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: modulation by kinases.Heterodimerization with the prostacyclin receptor triggers thromboxane receptor relocation to lipid rafts.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Membrane cholesterol affects stimulus-activity coupling in type 1, but not type 2, CCK receptors: use of cell lines with elevated cholesterol.Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levelsMolecular Pharmacology of δ-Opioid Receptors.Membrane Cholesterol Modulates LOX-1 Shedding in Endothelial CellsSarcolemmal dependence of cardiac protection and stress-resistance: roles in aged or diseased hearts.Delta Opioid Receptors and Cardioprotection.Allostery at opioid receptors: modulation with small molecule ligands.Chronic opioid treatment augments caveolin-1 scaffolding: relevance to stimulatory μ-opioid receptor adenylyl cyclase signaling.Down-regulation of c-Cbl by morphine accounts for persistent ERK1/2 signaling in delta-opioid receptor-expressing HEK293 cellsGPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles.Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins.
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P2860
Differential effect of membrane cholesterol removal on mu- and delta-opioid receptors: a parallel comparison of acute and chronic signaling to adenylyl cyclase
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differential effect of membran ...... signaling to adenylyl cyclase
@en
Differential effect of membran ...... signaling to adenylyl cyclase.
@nl
type
label
Differential effect of membran ...... signaling to adenylyl cyclase
@en
Differential effect of membran ...... signaling to adenylyl cyclase.
@nl
prefLabel
Differential effect of membran ...... signaling to adenylyl cyclase
@en
Differential effect of membran ...... signaling to adenylyl cyclase.
@nl
P2093
P2860
P356
P1476
Differential effect of membran ...... signaling to adenylyl cyclase
@en
P2093
Erica S Levitt
Jeffrey R Martens
John R Traynor
Mary J Clark
P2860
P304
22108-22122
P356
10.1074/JBC.M109.030411
P407
P577
2009-06-11T00:00:00Z