Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
about
Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediatorsImmunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesisA cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets WolbachiaAnti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasisAsymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissuesElevated adaptive immune responses are associated with latent infections of Wuchereria bancroftiWolbachia transcription elongation factor "Wol GreA" interacts with α2ββ'σ subunits of RNA polymerase through its dimeric C-terminal domainImmunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levelsNeutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective LarvaeNew insights into the evolution of Wolbachia infections in filarial nematodes inferred from a large range of screened speciesBoth asymmetric mitotic segregation and cell-to-cell invasion are required for stable germline transmission of Wolbachia in filarial nematodes.Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study.Lymphatic lipid transport: sewer or subway?Anti-filarial activity of antibiotic therapy is due to extensive apoptosis after Wolbachia depletion from filarial nematodes.Endosymbiotic bacteria associated with nematodes, ticks and amoebae.Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.The chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant miceLipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes.Human and animal dirofilariasis: the emergence of a zoonotic mosaic.Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus.Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.A potential role for the interaction of Wolbachia surface proteins with the Brugia malayi glycolytic enzymes and cytoskeleton in maintenance of endosymbiosisHuman filarial Wolbachia lipopeptide directly activates human neutrophils in vitroSoluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitmentAn overview on the field of micro- and nanotechnologies for synthetic Peptide-based vaccinesCirculating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection.Exome and transcriptome sequencing of Aedes aegypti identifies a locus that confers resistance to Brugia malayi and alters the immune response.Revisiting the Gram-negative lipoprotein paradigm.Filarial lymphatic pathology reflects augmented toll-like receptor-mediated, mitogen-activated protein kinase-mediated proinflammatory cytokine production.A feedback loop between Wolbachia and the Drosophila gurken mRNP complex influences Wolbachia titer.Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti-wolbachial treatment of the human host.Granulocytes in helminth infection -- who is calling the shots?Toll-like receptor- and filarial antigen-mediated, mitogen-activated protein kinase- and NF-κB-dependent regulation of angiogenic growth factors in filarial lymphatic pathology.Defining Brugia malayi and Wolbachia symbiosis by stage-specific dual RNA-seq.Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis.Recombinant Wolbachia heat shock protein 60 (HSP60) mediated immune responses in patients with lymphatic filariasis.The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models.Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.Alternative activation of macrophages by filarial nematodes is MyD88-independent.Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis
P2860
Q27304880-03647234-E95B-4C1D-AB3B-CC5C547D08EFQ27305577-9C7E4F58-5921-4CCA-80BA-7ADCC685C319Q27342384-B72666C2-88B2-472E-85AC-962D3D8F9629Q28294770-91744329-3F04-4504-8E21-6D49735859D2Q28474923-F66E49F7-E79F-4589-AE08-37AFBE9B175FQ28482086-A702E87A-993B-4379-B305-FB2BFD52B420Q28539855-E9E73CF3-A568-46F7-A7C1-DB0118D85C81Q28539936-AA2E0711-CE30-4F4B-ADC5-C63B461ADFF9Q28551578-35798AAF-5423-45ED-841D-541CDE5E14EBQ28743347-567FB8EF-99DE-46CB-B0D8-55E3DF577265Q30528769-39E732BD-0EBA-499D-8D5D-A4F1DA24CB16Q33888890-98240478-A1A5-45AD-B7FC-451BBFED904AQ34036806-8BE06B66-FEB8-45D1-8927-66583EE70179Q34071384-F05AF9BE-33A7-43EE-B67C-2B465DABACBAQ34086072-2A621B23-0E17-4872-B774-8B56A2731AA8Q34198127-58F9D91A-0775-4571-8EFE-1B6864310C0FQ34236931-919EF2F0-8993-4AF3-A6B0-D36AB4B7E71BQ34243810-FEF83CCB-881F-4037-980D-1A72D7A42649Q34327101-E1140BB7-D315-4608-BC2E-3E0DB5BDA5C3Q34339870-74A46F80-914B-43D2-813C-5821508C40E5Q34500870-A0945E0A-40FD-474D-A2EA-600A2969B2A6Q34675099-84CBE7EE-057F-4822-BACD-AC4E948531DAQ34805265-44D444EB-ED55-4122-B687-CCB34467270CQ34975511-EC42F381-2BC4-4926-BDCB-E7DAAAD0A725Q35100779-7231CE08-B6B4-427F-AE42-78D86959A1E6Q35156780-EDFD364D-2F4E-43C8-A74B-64AA964BD285Q35225265-314E080F-D739-4715-9271-67D8B47DF6E6Q35474434-61C3E3EE-9052-4244-841C-D55E438A4D24Q35671666-2397D2C4-D30C-44AC-AF5E-27D995C33812Q35672139-676956C8-03D9-42B8-A791-38A1C5E6E67FQ35848894-7A2A24DF-D29E-46A1-B1DF-615E8FC7AD11Q36088115-BF70CA09-A6D4-4FE9-93A0-67809B68EA62Q36156065-484CDBAB-B493-44BC-8107-43A74FA5C7EAQ36328350-01FF1158-34F9-4F66-AC6A-AB3BDCCB292EQ36446223-48665C2C-D0E4-46F0-8D34-2C8989C38814Q36448950-0C71AB3C-3283-48A0-BBF4-02971BCC2F1DQ36599857-64540836-97BF-4642-BFBA-A905B7E2B863Q36708214-80011E16-D1F6-4D6E-AE23-A32D5F81BCE9Q36715903-55FD2F96-F94B-40B1-8203-981075B6CFF6Q36732040-E8AA7085-3B82-43F4-A70B-DDC4C6214587
P2860
Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@en
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@nl
type
label
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@en
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@nl
prefLabel
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@en
Wolbachia lipoprotein stimulat ...... manifestations of filariasis.
@nl
P2093
P2860
P50
P921
P356
P1476
Wolbachia lipoprotein stimulat ...... e manifestations of filariasis
@en
P2093
Barton Slatko
Eric Pearlman
Faye Sharpley
Katrin Gentil
Kelly L Johnston
Maia Graham
R Stuart Langley
P2860
P304
22364-22378
P356
10.1074/JBC.M901528200
P407
P577
2009-05-19T00:00:00Z