A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
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Functional Brain Network Characterization and Adaptivity during Task Practice in Healthy Volunteers and People with SchizophreniaSchizophrenia and vitamin D related genes could have been subject to latitude-driven adaptationNeuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapseshERG channel function: beyond long QTGene expression profiling of the brain: pondering facts and fictionThe structural mechanism of KCNH-channel regulation by the eag domain.Major channels involved in neuropsychiatric disorders and therapeutic perspectivesPaternal age, de novo mutations and schizophreniaDisease-relevant autoantibodies in first episode schizophreniaInhibition of HERG potassium channels by celecoxib and its mechanismIntegrated analysis of drug-induced gene expression profiles predicts novel hERG inhibitorsQT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjectsSpatio-temporal transcriptome of the human brainAntiarrhythmics cure brain arrhythmia: The imperativeness of subthalamic ERG K+ channels in parkinsonian discharges.Advancing drug discovery for schizophrenia.Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing.SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments.Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.Category fluency, latent semantic analysis and schizophrenia: a candidate gene approachMolecular mechanism of voltage-dependent potentiation of KCNH potassium channelsMultimodal white matter imaging to investigate reduced fractional anisotropy and its age-related decline in schizophreniaTwo four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: a case control study.Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.Prenatal expression patterns of genes associated with neuropsychiatric disorders.Alternative splicing and polyadenylation contribute to the generation of hERG1 C-terminal isoformsIdentification of Kv11.1 isoform switch as a novel pathogenic mechanism of long-QT syndrome.Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channelsAnalyzing schizophrenia by DNA microarraysGenetic neuropathology of obsessive psychiatric syndromes.Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity.The schizophrenia-associated Kv11.1-3.1 isoform results in reduced current accumulation during repetitive brief depolarizations.A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.hERG potassium channel gating is mediated by N- and C-terminal region interactionsNext-generation treatments for mental disorders."Attenuated psychotic symptoms syndrome" as a risk syndrome of psychosis, diagnosis in DSM-V: The debatePersonalized medicine in psychiatry: problems and promises.Gene expression profiling in rodent models for schizophrenia.Psychiatric brain banking: three perspectives on current trends and future directions.An evaluation of association between a novel hippocampal biology related SNP (rs7294919) and schizophrenia.Intermediate phenotypes in psychiatric disorders.
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A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A primate-specific, brain isof ...... tion and risk of schizophrenia
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A primate-specific, brain isof ...... ion and risk of schizophrenia.
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type
label
A primate-specific, brain isof ...... tion and risk of schizophrenia
@en
A primate-specific, brain isof ...... ion and risk of schizophrenia.
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prefLabel
A primate-specific, brain isof ...... tion and risk of schizophrenia
@en
A primate-specific, brain isof ...... ion and risk of schizophrenia.
@nl
P2093
P2860
P50
P356
P1433
P1476
A primate-specific, brain isof ...... tion and risk of schizophrenia
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P2093
Alessandro Bertolino
Armen Soghoyan
Barbara K Lipska
Grazia Caforio
Jingshan Chen
Joel E Kleinman
P2860
P2888
P304
P356
10.1038/NM.1962
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P50
P577
2009-05-03T00:00:00Z