The amino acid sequences flanking an antigenic determinant can strongly affect MHC class I cross-presentation without altering direct presentation.
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Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsDirect presentation is sufficient for an efficient anti-viral CD8+ T cell response.High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protectionDirect presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation.Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation.Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma.
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The amino acid sequences flanking an antigenic determinant can strongly affect MHC class I cross-presentation without altering direct presentation.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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The amino acid sequences flank ...... altering direct presentation.
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Amparo Serna
Ren-Huan Xu
Xueying Ma
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10.4049/JIMMUNOL.0803806
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P50
P577
2009-04-01T00:00:00Z