Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
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The complex and central role of interferon-γ in graft-versus-host disease and graft-versus-tumor activityAcute graft-versus-host disease: a bench-to-bedside update.The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical OverviewCurrent data on IL-17 and Th17 cells and implications for graft versus host disease.Kinetics of IFN-γ and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease.Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationInterleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target.Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effectsThe biology of graft-versus-host disease: experimental systems instructing clinical practice.SOCS3 regulates graft-versus-host disease.Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses.A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation.Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance.Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect.Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance.Th17/Treg ratio in human graft-versus-host disease.GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppressionDecreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation.Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.Blockade of lymphocyte chemotaxis in visceral graft-versus-host disease.Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host diseaseThe role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host diseaseIL-17 enhances tumor development in carcinogen-induced skin cancer.Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation.B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft-versus-host diseaseT-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and functionIndoleamine 2,3-dioxygenase in human hematopoietic stem cell transplantation.Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen.Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in miceImmune Reconstitution Kinetics following Intentionally Induced Mixed Chimerism by Nonmyeloablative Transplantation.Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethality.Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice.Adoptive Transfer of Treg Cells Combined with Mesenchymal Stem Cells Facilitates Repopulation of Endogenous Treg Cells in a Murine Acute GVHD Model.In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation.Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice.
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Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Reciprocal differentiation and ...... s in graft-versus-host disease
@en
Reciprocal differentiation and ...... in graft-versus-host disease.
@nl
type
label
Reciprocal differentiation and ...... s in graft-versus-host disease
@en
Reciprocal differentiation and ...... in graft-versus-host disease.
@nl
prefLabel
Reciprocal differentiation and ...... s in graft-versus-host disease
@en
Reciprocal differentiation and ...... in graft-versus-host disease.
@nl
P2093
P2860
P1433
P1476
Reciprocal differentiation and ...... s in graft-versus-host disease
@en
P2093
Dale T Umetsu
Daniel Huang
Dongchang Zhao
Fouad Kandeel
Heather Johnston
Ivan Todorov
James Young
Lieping Chen
P2860
P304
P356
10.1182/BLOOD-2009-05-219402
P407
P577
2009-07-14T00:00:00Z