A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.
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Targeting androgen receptor and JunD interaction for prevention of prostate cancer progressionThe Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung CancerPretreatment with anti-oxidants sensitizes oxidatively stressed human cancer cells to growth inhibitory effect of suberoylanilide hydroxamic acid (SAHA).A microfluidic coculture and multiphoton FAD analysis assay provides insight into the influence of the bone microenvironment on prostate cancer cellsAndrogen receptor requires JunD as a coactivator to switch on an oxidative stress generation pathway in prostate cancer cells.Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines.Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen speciesOxidative stress measured by urine F2-isoprostane level is associated with prostate cancerIncreased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.STAMP2 increases oxidative stress and is critical for prostate cancer.Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesisFrequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells.Redox-mediated and ionizing-radiation-induced inflammatory mediators in prostate cancer development and treatment.Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism.Effects of astaxanthin on oxidative stress induced by Cu2+ in prostate cells.A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer.Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines.Expression of spermidine/spermine N(1) -acetyl transferase (SSAT) in human prostate tissues is related to prostate cancer progression and metastasis.Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy.Lipid peroxidation product acrolein as a predictive biomarker of prostate carcinoma relapse after radical surgery.Deviations of the immune cell landscape between healthy liver and hepatocellular carcinoma.
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P2860
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A small molecule polyamine oxi ...... a of the mouse prostate model.
@en
A small molecule polyamine oxi ...... a of the mouse prostate model.
@nl
type
label
A small molecule polyamine oxi ...... a of the mouse prostate model.
@en
A small molecule polyamine oxi ...... a of the mouse prostate model.
@nl
prefLabel
A small molecule polyamine oxi ...... a of the mouse prostate model.
@en
A small molecule polyamine oxi ...... a of the mouse prostate model.
@nl
P2093
P2860
P1433
P1476
A small molecule polyamine oxi ...... a of the mouse prostate model.
@en
P2093
Christopher T Martin
Corey A Amlong
Cynthia C Clower
Dawn R Church
Farideh Mehraein-Ghomi
Hirak S Basu
Mary J Lindstrom
Todd A Thompson
P2860
P304
P356
10.1158/0008-5472.CAN-08-2472
P407
P577
2009-09-22T00:00:00Z