Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase.
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Potential use of rapamycin in HIV infectionNovel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOREndothelial Cell mTOR Complex-2 Regulates Sprouting AngiogenesisClinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: a phase II trial (CTEP 7190/Mel47)Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway.Hantavirus interferon regulation and virulence determinantsVirus interactions with endothelial cell receptors: implications for viral pathogenesis.Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in miceIdentification and functional analysis of endothelial tip cell-enriched genesRegulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.Heterogeneity of the tumor vasculature.Anti-VEGF/VEGFR therapy for cancer: reassessing the target.Mammalian target of rapamycin signaling in diabetic cardiovascular diseaseN-carbamylglutamate enhances pregnancy outcome in rats through activation of the PI3K/PKB/mTOR signaling pathway.Andes virus infection of lymphatic endothelial cells causes giant cell and enhanced permeability responses that are rapamycin and vascular endothelial growth factor C sensitive.Insulin-like growth factor binding protein-3 suppresses vascular endothelial growth factor expression and tumor angiogenesis in head and neck squamous cell carcinoma.Rapamycin Protects from Type-I Peritoneal Membrane Failure Inhibiting the Angiogenesis, Lymphangiogenesis, and Endo-MT.Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targetsLY2228820 dimesylate, a selective inhibitor of p38 mitogen-activated protein kinase, reduces angiogenic endothelial cord formation in vitro and in vivo.Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway.Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B.Adventitial nab-rapamycin injection reduces porcine femoral artery luminal stenosis induced by balloon angioplasty via inhibition of medial proliferation and adventitial inflammation.Hsp90β promoted endothelial cell-dependent tumor angiogenesis in hepatocellular carcinoma.Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases.Selectively starving cancer cells through dietary manipulation: methods and clinical implications.Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.Role of vascular and lymphatic endothelial cells in hantavirus pulmonary syndrome suggests targeted therapeutic approaches.The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches.Chemoprevention of age-related macular regeneration (AMD) with rapamycin.mTOR co-targeting strategies for head and neck cancer therapyR-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature.Glucocorticoid effects on angiogenesis are associated with mTOR pathway activity.Hypoxia-induced autophagy in endothelial cells: a double-edged sword in the progression of infantile haemangioma?Treatment of voluminous and complicated superficial slow-flow vascular malformations with sirolimus (PERFORMUS): protocol for a multicenter phase 2 trial with a randomized observational-phase design.
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P2860
Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@en
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@nl
type
label
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@en
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@nl
prefLabel
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@en
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@nl
P2093
P2860
P1476
Rapamycin inhibition of the Ak ...... in part by blocking S6Kinase.
@en
P2093
Eleanor J Manseau
Harold F Dvorak
Janice A Nagy
Laura E Benjamin
Thuy L Phung
P2860
P304
P356
10.1161/ATVBAHA.109.185918
P407
P577
2009-05-14T00:00:00Z