Thermal stability threshold for amyloid formation in light chain amyloidosis.
about
Differential effects on light chain amyloid formation depend on mutations and type of glycosaminoglycansStability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the VL framework using a structure-guided approachDifferential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils-A metric for predicting amyloid propensity.Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding.In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.Recruitment of Light Chains by Homologous and Heterologous Fibrils Shows Distinctive Kinetic and Conformational Specificity.Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation.Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate.Mutations can cause light chains to be too stable or too unstable to form amyloid fibrils.Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING.Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains.A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation.
P2860
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P2860
Thermal stability threshold for amyloid formation in light chain amyloidosis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@en
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@nl
type
label
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@en
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@nl
prefLabel
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@en
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@nl
P2093
P2860
P356
P1476
Thermal stability threshold for amyloid formation in light chain amyloidosis.
@en
P2093
Marina Ramirez-Alvarado
Nagaaki Katoh
Tanya L Poshusta
P2860
P304
22604-22617
P356
10.3390/IJMS141122604
P407
P577
2013-11-15T00:00:00Z