In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression.
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Molecular mechanisms of biological aging in intervertebral discsDiversity of intervertebral disc cells: phenotype and functionChallenges and strategies in the repair of ruptured annulus fibrosusExpression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degenerationMechanical design criteria for intervertebral disc tissue engineeringLong-term load duration induces N-cadherin down-regulation and loss of cell phenotype of nucleus pulposus cells in a disc bioreactor cultureCellular mechanobiology of the intervertebral disc: new directions and approaches.Analysis of the load on the knee joint and vertebral column with changes in squatting depth and weight load.Region-dependent aggrecan degradation patterns in the rat intervertebral disc are affected by mechanical loading in vivo.In vivo and in vitro analysis of rat lumbar spine mechanicsDynamic and static overloading induce early degenerative processes in caprine lumbar intervertebral discs.Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.Region specific response of intervertebral disc cells to complex dynamic loading: an organ culture study using a dynamic torsion-compression bioreactor.Integrin - dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degenerationDose-dependent response of tissue-engineered intervertebral discs to dynamic unconfined compressive loading.Complex loading affects intervertebral disc mechanics and biologyPhysiological loading can restore the proteoglycan content in a model of early IVD degeneration.Intervertebral disc changes with angulation, compression and reduced mobility simulating altered mechanical environment in scoliosisPenetrating annulus fibrosus injuries affect dynamic compressive behaviors of the intervertebral disc via altered fluid flow: an analytical interpretationPhysical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disabilityBrief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner.The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degenerationRat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degenerationStatic axial overloading primes lumbar caprine intervertebral discs for posterior herniation.Dynamic Compression Effects on Immature Nucleus Pulposus: a Study Using a Novel Intelligent and Mechanically Active Bioreactor.Cervical disc deformation during flexion-extension in asymptomatic controls and single-level arthrodesis patients.Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells?METABOLIC EFFECTS OF ANGULATION, COMPRESSION AND REDUCED MOBILITY ON ANNULUS FIBROSIS IN A MODEL OF ALTERED MECHANICAL ENVIRONMENT IN SCOLIOSIS.Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells.17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.The effects of dynamic loading on the intervertebral disc.Biomechanics of intervertebral disk degeneration.Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level.Duration-dependent influence of dynamic torsion on the intervertebral disc: an intact disc organ culture study.Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs.Fas ligand plays an important role for the production of pro-inflammatory cytokines in intervertebral disc nucleus pulposus cells.Translation of an engineered nanofibrous disc-like angle-ply structure for intervertebral disc replacement in a small animal model.A Well-Controlled Nucleus Pulposus Tissue Culture System with Injection Port for Evaluating Regenerative Therapies.Preconditioning of mesenchymal stromal cells toward nucleus pulposus-like cells by microcryogels-based 3D cell culture and syringe-based pressure loading system.
P2860
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P2860
In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
In vivo remodeling of interver ...... long-term dynamic compression.
@en
In vivo remodeling of interver ...... long-term dynamic compression.
@nl
type
label
In vivo remodeling of interver ...... long-term dynamic compression.
@en
In vivo remodeling of interver ...... long-term dynamic compression.
@nl
prefLabel
In vivo remodeling of interver ...... long-term dynamic compression.
@en
In vivo remodeling of interver ...... long-term dynamic compression.
@nl
P2093
P2860
P356
P1476
In vivo remodeling of interver ...... long-term dynamic compression.
@en
P2093
Ana Barbir
Jeffrey J MacLean
Justin Stinnett Donnelly
Karolyn Godburn
Mauro Alini
Peter J Roughley
P2860
P304
P356
10.1002/JOR.20867
P577
2009-09-01T00:00:00Z